DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-epsilon and olfml2ba

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_001038314.1	Gene:	olfml2ba / 557997	ZFINID:	ZDB-GENE-041014-329	Length:	883	Species:	Danio rerio

Alignment Length:	516	Identity:	100/516 - (19%)
Similarity:	160/516 - (31%)	Gaps:	179/516 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 YHLEAISSFLYVGLGCLIASSVALSTDTGS-------EGNAGNVGGST----------------L 44
            |.:|.|:|..:....| ||...||:...|.       :....|:..||                |
Zfish    96 YTVETITSGPHCKCAC-IAPPSALNPCEGDFRLKKLRQAGKDNIKLSTILELLEGSFYGMDLLKL 159

  Fly    45 NNVISEDPEFTDVIENI-----------TVPAGRNVKLA---------------CSVKNLGSYKV 83
            ::|.::..:..|.||.:           |:....|.:|:               .|::.......
Zfish   160 HSVTTKILDRMDTIEKMVLNNQTEEKLNTISTSPNPQLSTSSPTTLPSVIQEKRTSLREQNDEAA 224

  Fly    84 AWMHFEQSAILTVHNHVITRNPRISVTHDKHDKHRTWFL--------HINNV-----QEEDRGRY 135
            |:.|.|..::|..               .:..|:...|:        .:|..     ::|.:||.
Zfish   225 AFQHMEYYSVLKC---------------TQQSKYEEKFVGDILNSGSDLNKATTALQEQEQQGRK 274

  Fly   136 MCQINTVTAKTQY---GFVKVVVPPNIDDALTSSDIIVREGDNVTLRCKAKGSPEPTIK-WKRDD 196
            .....||...|.|   ...::....|:||.|:....|....|...||.||:.. .|.|| |....
Zfish   275 KQPKITVRGITYYRSDPVDEMDSEKNLDDNLSGDSPIDLFADEQLLRHKARHF-RPVIKAWSVRP 338

  Fly   197 GNKIVINK---------------------------------TLEVH---DLET------------ 213
            ..|..|:|                                 |...|   |..|
Zfish   339 KTKSEISKGGDAPKKHQNPLMGLLDSTALPIKTPTEPITVQTQTSHSTTDSSTGDERTTTTPAAM 403

  Fly   214 DSLELERISRLHMGAYLCIASNGV---PPSVSKRIKVSVDFSPMVWIPHQLVGIPIGFNITLECF 275
            |:|::.:.|...|.|      |.|   .|||.:...:.|..|       .|..|....::.....
Zfish   404 DNLKVTKSSIKRMEA------NKVEPPTPSVQQAQNMLVRSS-------NLGHIKTNESVAAAVK 455

  Fly   276 IEA-NPTSLNYWTRENDQMITESSKYK-TET---IPGHPSYKATMRLTITNVQSS--DYGNYKCV 333
            :|| .||..|   :.|...:.|:|... |:|   |..|  .||:.:.|:..:..|  .:.|...|
Zfish   456 VEATEPTMTN---QTNGTAVKETSASSVTQTGALIKEH--LKASTQSTLNTLTPSPTSHSNALTV 515

  Fly   334 AKNP------RGDM--------------DGNIKLYMSSPPTTQPPPTTTTLRRTTTTAAEI 374
            .::.      :|::              |....|...||...:...||.|..:|.||:..:
Zfish   516 TESSVGINAHKGEVTTIVMTASVTGSKTDSVTDLTQLSPRVRETLTTTRTTTKTATTSQPV 576

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	19/137 (14%)
		Ig	69..139	CDD:143165	12/97 (12%)
		IG_like	165..249	CDD:214653	27/135 (20%)
		IGc2	172..237	CDD:197706	22/113 (19%)
		IG_like	267..348	CDD:214653	20/107 (19%)
		Ig	270..339	CDD:299845	18/81 (22%)
olfml2ba	NP_001038314.1	PHA03255	450..>584	CDD:165513	29/132 (22%)
olfml2ba	NP_001038314.1	OLF	625..875	CDD:280371
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm26286
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000