DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-epsilon and Pxdn

DIOPT Version :9

Sequence 1:NP_001137799.1 Gene:DIP-epsilon / 7354433 FlyBaseID:FBgn0259714 Length:467 Species:Drosophila melanogaster
Sequence 2:NP_001258190.1 Gene:Pxdn / 554172 RGDID:1560694 Length:1475 Species:Rattus norvegicus


Alignment Length:375 Identity:93/375 - (24%)
Similarity:162/375 - (43%) Gaps:58/375 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    27 STDTGSEG----NAGNVGGSTLNNVIS-------EDPEFTDVIENITVPAGRNVKLACSVKNLGS 80
            :|....||    .|.||.|....:.::       ..|.|....:|..|..|.:|.|.||......
  Rat   303 NTQEADEGVYQCMAKNVAGEAKTHEVTLRYLGSPARPTFVIQPQNTEVLVGESVTLECSATGHPL 367

  Fly    81 YKVAWMHFEQSAILTVHNHVITRNPRISVTHDKHDKHRTWFLHINNVQEEDRGRYMC-QINTVTA 144
            .::.|...:::.        :..:||:::|       .:..|:|.||.:.|.|.|.| ..|:|.:
  Rat   368 PQITWTRGDRTP--------LPIDPRVNIT-------PSGGLYIQNVAQSDSGEYTCFASNSVDS 417

  Fly   145 KTQYGFVKVVVPPNIDDALTSSDIIVREGDNVTLRCKAKGSPEPTIKWKRDDGNKIVINKTLEVH 209
            .....|:.|...|..  .:|....:|.||..|..:|:|||.|:|.|.|.: .|:::.:::...| 
  Rat   418 IHATAFIIVQALPQF--TVTPQSRVVIEGQTVDFQCEAKGYPQPVIAWTK-GGSQLSVDRRHLV- 478

  Fly   210 DLETDSLELERISRLHMGAYLCIASNGVPPSVSKRIKVSVDFSPMVW-----IPHQLVGIPIGFN 269
             |.:.:|.:..::....|.|.|.|.|.:.   |:::...:...|.|.     ||..:. :.:|.|
  Rat   479 -LSSGTLRISGVALHDQGQYECQAVNIIG---SQKVVAHLTVQPRVTPVFASIPSDMT-VEVGTN 538

  Fly   270 ITLECFIEANPTSLNYWTRENDQMITESSKYKTETIPGHPSYKATMRLTITNVQSSDYGNYKCVA 334
            :.|.|..:..|.....|.::..| :|||.|:       |.|.:..  |||.:|.::|.|.|:|||
  Rat   539 VQLPCSSQGEPEPAITWNKDGVQ-VTESGKF-------HISPEGF--LTINDVGTADAGRYECVA 593

  Fly   335 KNPRGDMDGNIKLYMSSPPTTQ--PPPTTTTLRRTTTTAAEIALDGYINT 382
            :|..|....::.|.::.|..::  .|...|::.....|     :|..||:
  Rat   594 RNTIGYASVSMVLSVNVPDVSRNGDPYVATSIVEAIAT-----VDRAINS 638

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-epsilonNP_001137799.1 IG_like 59..155 CDD:214653 23/96 (24%)
Ig 69..139 CDD:143165 16/70 (23%)
IG_like 165..249 CDD:214653 22/83 (27%)
IGc2 172..237 CDD:197706 20/64 (31%)
IG_like 267..348 CDD:214653 25/80 (31%)
Ig 270..339 CDD:299845 22/68 (32%)
PxdnNP_001258190.1 leucine-rich repeat 42..60 CDD:275380
leucine-rich repeat 63..84 CDD:275380
LRR_4 107..148 CDD:289563
LRR_8 108..167 CDD:290566
leucine-rich repeat 109..132 CDD:275378
LRR_4 132..172 CDD:289563
leucine-rich repeat 133..156 CDD:275378
LRR_8 155..>192 CDD:290566
leucine-rich repeat 157..180 CDD:275378
leucine-rich repeat 181..193 CDD:275378
TPKR_C2 189..240 CDD:301599
Ig 243..330 CDD:299845 7/26 (27%)
I-set 243..330 CDD:254352 7/26 (27%)
I-set 339..426 CDD:254352 24/101 (24%)
Ig 343..426 CDD:299845 22/97 (23%)
I-set 430..516 CDD:254352 24/93 (26%)
Ig3_Peroxidasin 443..516 CDD:143222 21/78 (27%)
I-set 522..608 CDD:254352 28/96 (29%)
Ig4_Peroxidasin 539..607 CDD:143223 23/77 (30%)
An_peroxidase 738..1279 CDD:281139
peroxidasin_like 861..1300 CDD:188658
VWC 1411..1466 CDD:214564
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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