DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-epsilon and Pvr

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_081790.1	Gene:	Pvr / 52118	MGIID:	107741	Length:	408	Species:	Mus musculus

Alignment Length:	363	Identity:	75/363 - (20%)
Similarity:	118/363 - (32%)	Gaps:	124/363 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 NITVPAGRNVKLACSV---KNLGSYKVAWMHFEQSAILTVHNHVITRNPRISVTHDK-----HDK 116
            |.|...|.:..|.||:   :|:...::.||..:...     :|.:     ::|.|.|     .:.
Mouse    37 NSTGVLGGSTTLHCSLTSNENVTITQITWMKKDSGG-----SHAL-----VAVFHPKKGPNIKEP 91

  Fly   117 HRTWF-----------LHINNVQEEDRGRYMCQINTVT--AKTQYGFVKVVV-PPNIDDALTSSD 167
            .|..|           |.|:|:..||.|.|.|||.|..  :::...::||.. |.|..:||..|.
Mouse    92 ERVKFLAAQQDLRNASLAISNLSVEDEGIYECQIATFPRGSRSTNAWLKVQARPKNTAEALEPSP 156

  Fly   168 IIVREGDNVTLRCKAKGSPEPTIKW--------------------------------KRDDGNKI 200
            .::.:  :|.....|.|.|...|.|                                ::.||..|
Mouse   157 TLILQ--DVAKCISANGHPPGRISWPSNVNGSHREMKEPGSQPGTTTVTSYLSMVPSRQADGKNI 219

  Fly   201 VINKTLEVHDLETDSLELERISRLHMGAYLCIASNGVPPSVSKRIKVSVDFSPMVWIPHQLVGIP 265
            ..  |:|...|:    ||:::        |...|...||.     .||:......|    .||:.
Mouse   220 TC--TVEHESLQ----ELDQL--------LVTLSQPYPPE-----NVSISGYDGNW----YVGLT 261

  Fly   266 IGFNITLECFIEANP----TSLNYWTRENDQMITESSKYKTETIPGHPSYKATMRL--------- 317
               |:||.|...:.|    ...|:.|...|             .|.....:..|.|
Mouse   262 ---NLTLTCEAHSKPAPDMAGYNWSTNTGD-------------FPNSVKRQGNMLLISTVEDGLN 310

  Fly   318 ------TITNVQSSDYGNYKCVAKNPRGDMDGNIKLYM 349
                  .:||...|..|....:.|....:|..|.:|::
Mouse   311 NTVIVCEVTNALGSGQGQVHIIVKEKPENMQQNTRLHL 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	28/115 (24%)
		Ig	69..139	CDD:143165	20/88 (23%)
		IG_like	165..249	CDD:214653	20/115 (17%)
		IGc2	172..237	CDD:197706	16/96 (17%)
		IG_like	267..348	CDD:214653	18/99 (18%)
		Ig	270..339	CDD:299845	15/87 (17%)
Pvr	NP_081790.1	IG_like	35..141	CDD:214653	26/113 (23%)
		Ig1_PVR_like	44..142	CDD:143195	24/107 (22%)
		Ig2_Nectin-2_like	145..240	CDD:143327	20/110 (18%)
		IG_like	262..333	CDD:214653	15/83 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910