DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-epsilon and CEACAM6

DIOPT Version :9

Sequence 1:NP_001137799.1 Gene:DIP-epsilon / 7354433 FlyBaseID:FBgn0259714 Length:467 Species:Drosophila melanogaster
Sequence 2:NP_002474.4 Gene:CEACAM6 / 4680 HGNCID:1818 Length:344 Species:Homo sapiens


Alignment Length:299 Identity:63/299 - (21%)
Similarity:107/299 - (35%) Gaps:70/299 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   122 LHINNVQEEDRGRYMCQI---NTVT--AKTQYGFVKVVVPPNIDDALTSSDIIVREGDNVTLRCK 181
            |.|.||.:.|.|.|..|:   :.|.  |..|:.....:..|:|.   :::...|.:.|.|...|:
Human   107 LLIQNVTQNDTGFYTLQVIKSDLVNEEATGQFHV
YPELPKPSIS---SNNSNPVEDKDAVAFTCE 168

  Fly   182 AKGSPEPTIKWKRDDGNKIVINKTLEVHDLETDSLELERISRLHMGAYLCIASNGVPPSVSKRIK 246
            .:......:.|.  :|..:.::..|::.: ...:|.|..:.|...|:|.|...|....:.|..:.
Human   169 PEVQNTTYLWWV--NGQSLPVSPRLQLSN-GNMTLTLLSVKRNDAGSYECEIQNPASANRSDPVT 230

  Fly   247 VSVDFSPMV-WIPHQLVGIPIGFNITLECFIEANPTSLNYWTRENDQMITESSKYKTETIPGHPS 310
            ::|.:.|.| .|.........|.|:.|.|...:||.:...|                 .|.| ..
Human   231 LNVL
YGPDVPTISPSKANYRPGENLNLSCHAASNPPAQYSW-----------------FING-TF 277

  Fly   311 YKATMRLTITNVQSSDYGNYKCVAKNPRGDMDGNIKLYMSSPPTTQPPPTTTTLRRTTTTAAEIA 375
            .::|..|.|.|:..::.|:|.|.|.|                       :.|.|.|||.|.    
Human   278 QQSTQELFIPNITVNNSGSYMCQAHN-----------------------SATGLNRTTVTM---- 315

  Fly   376 LDGYINTPLNGNGIGIVGEGPTNSVIASGKSSIKYLSNL 414
                         |.:.|..|..|.:|:...:|..|:.:
Human   316 -------------ITVSGSAPVLSAVATVGITIGVLARV 341

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-epsilonNP_001137799.1 IG_like 59..155 CDD:214653 11/37 (30%)
Ig 69..139 CDD:143165 7/16 (44%)
IG_like 165..249 CDD:214653 15/83 (18%)
IGc2 172..237 CDD:197706 13/64 (20%)
IG_like 267..348 CDD:214653 18/80 (23%)
Ig 270..339 CDD:299845 16/68 (24%)
CEACAM6NP_002474.4 IgV_CEACAM_D1 36..140 CDD:409430 11/32 (34%)
Ig strand B 51..55 CDD:409430
Ig strand C 64..68 CDD:409430
Ig strand E 105..109 CDD:409430 1/1 (100%)
Ig strand F 119..124 CDD:409430 1/4 (25%)
Ig strand G 133..136 CDD:409430 1/2 (50%)
IgI_hCEACAM_2_4_6_like 146..234 CDD:409402 17/93 (18%)
Ig strand B 163..167 CDD:409402 1/3 (33%)
Ig strand C 176..180 CDD:409402 0/3 (0%)
Ig strand E 198..202 CDD:409402 1/3 (33%)
Ig strand F 212..217 CDD:409402 2/4 (50%)
Ig strand G 227..230 CDD:409402 0/2 (0%)
IgC2_CEACAM5-like 243..318 CDD:409540 25/132 (19%)
Ig strand B 255..259 CDD:409540 1/3 (33%)
Ig strand C 268..272 CDD:409540 1/20 (5%)
Ig strand E 285..289 CDD:409540 1/3 (33%)
Ig strand F 296..301 CDD:409540 2/4 (50%)
Ig strand G 311..314 CDD:409540 2/2 (100%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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