DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-epsilon and dpr13

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_001033956.2	Gene:	dpr13 / 3885598	FlyBaseID:	FBgn0034286	Length:	419	Species:	Drosophila melanogaster

Alignment Length:	231	Identity:	62/231 - (26%)
Similarity:	102/231 - (44%)	Gaps:	35/231 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 LSTDTGSEGNAGNVGGS-----TLNNVISEDPEFTDVIENITVPAGRNVKLACSVKNLGSYKVAW 85
            |..:.|.||...::.|:     |.|:.:            :|...|....:.|:|.::|...|:|
  Fly   157 LEANNGIEGGMESLFGTPMYFGTENSTV------------VTTQIGATAHVPCTVHHIGEGVVSW 209

  Fly    86 MHFEQSAILTVHNHVITRNPRISVTHDKHDKHRTWFLHINNVQEEDRGRYMCQINTVTAKTQYGF 150
            :..:...:|||.....:.:.|.|.||.||.:  .|.|.|..||..|.|.|.||::|....:.:..
  Fly   210 IRKKDYHLLTVGLTTYSSDERFSATHLKHSE--DWTLQIKFVQLRDAGVYECQVSTHPPTSIFLH 272

  Fly   151 VKVVVPPNIDDALTSSDI-IVREGDNVTLRCKAKGSPEPT--IKWKRDDGNKIV-------INKT 205
            :.||   .....:|...| .:..|..:.|:|:...:.|.:  |.|..|  |:::       ||.:
  Fly   273 LSVV---EARAEITGPPIRYLTPGSTLRLQCRVVQNTEASEYIFWYHD--NRMINYDIDRGINVS 332

  Fly   206 LEVHDLETDSLELERISRLHMGAYLCIASNGVPPSV 241
            .| .|.::..|.::|..|.|.|.:.|:|||..|.||
  Fly   333 TE-PDFQSSELTIQRTRREHSGNFTCVASNTQPASV 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	28/95 (29%)
		Ig	69..139	CDD:143165	23/69 (33%)
		IG_like	165..249	CDD:214653	25/87 (29%)
		IGc2	172..237	CDD:197706	21/73 (29%)
		IG_like	267..348	CDD:214653
		Ig	270..339	CDD:299845
dpr13	NP_001033956.2	V-set	180..276	CDD:284989	28/109 (26%)
		IG_like	182..262	CDD:214653	26/93 (28%)
		IG_like	285..362	CDD:214653	21/79 (27%)
		IGc2	292..361	CDD:197706	19/71 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I11916
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810