DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-epsilon and Dscam2

DIOPT Version :9

Sequence 1:NP_001137799.1 Gene:DIP-epsilon / 7354433 FlyBaseID:FBgn0259714 Length:467 Species:Drosophila melanogaster
Sequence 2:NP_001261500.1 Gene:Dscam2 / 38788 FlyBaseID:FBgn0265296 Length:2101 Species:Drosophila melanogaster


Alignment Length:425 Identity:101/425 - (23%)
Similarity:164/425 - (38%) Gaps:68/425 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    17 GCLIASSVALSTDTG--------SEGNAGNVGGSTLNNVISEDPEFTDVIENI-TVPAGRNVKLA 72
            |.|..|.|..::|:|        .:|::....|..   .:...|:.:....|| .:..|....|.
  Fly   572 GSLTISPVQKNSDSGVYTCWARNKQGHSARRSGEV---TVIVPPKLSPFQTNILQLNMGDRASLT 633

  Fly    73 CS-VKNLGSYKVAWMHFEQSAILTVHNHVITRNPRISVTHDKHDKHRTWFLHINNVQEEDRGRYM 136
            || ||......:.|....:....|.|..|           .:.|::.: .|.|.|:..:..|.|.
  Fly   634 CSVVKGDLPLTINWRKDGRPIDPTQHMSV-----------KQVDQYNS-ILVIENLGSDHTGNYS 686

  Fly   137 CQINTVTAKTQYGFVKVV-VPPNIDDALTSSDIIVREGDNVTLRCKAKGSPEPTIKWKRDDGNKI 200
            |.:....|:.:.....:| |||..  .:...|..|....::.|.|:|:|.|.|:|.||:..|:| 
  Fly   687 CVVRNSAAEVENSQALLVNVPPRW--IVEPVDANVERNRHIMLHCQAQGVPTPSIVWKKATGSK- 748

  Fly   201 VINKTLEVHD------LETDSLELERISRLHMGAYLCIASNGVPPSVSKRIKVSVDFSPMVWIPH 259
             ..:..||.:      |...||.|:.:.....|.|||.|:||:...:.|.|::.|:.||......
  Fly   749 -SGEYEEVRERPFTKLLGNGSLLLQHVKEDREGFYLCQANNGIGTGIGKVIQLKVNSSPYFSSTS 812

  Fly   260 QLVGIPIGFNITLECFIEANPTSLNYWTRENDQMITESSKY----KTETIPGHPSYKATMRLTIT 320
            :.|.:..|....|:|.:..:......|.|.....:..|:.|    |.|..|...|    ..|.|.
  Fly   813 RSVMVKKGDTALLQCAVSGDKPINIVWMRSGKNTLNPSTNYKISVKQEATPDGVS----AELQIR 873

  Fly   321 NVQSSDYGNYKCVAKNPRGDMDGNIKLYMSSPPTTQPPPTTTTLRRTTTTAAEIALDGYINTPLN 385
            .|.::|.|.|.|.|.|..|:....::|.:..||.   ||          :..|.|:       ::
  Fly   874 TVDATDSGPYFCRASNLYGNDQQLVQLQVQEPPL---PP----------SVLEAAM-------IS 918

  Fly   386 GNGIGIVGEGPTNSVIASGKSSIKYLSNLNEIDKS 420
            ...:.|..:..|   :.:|..: ||:....|.|.|
  Fly   919 SRSVNIKWQPKT---LGTGDVT-KYIVEFREADHS 949

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-epsilonNP_001137799.1 IG_like 59..155 CDD:214653 21/98 (21%)
Ig 69..139 CDD:143165 16/70 (23%)
IG_like 165..249 CDD:214653 28/89 (31%)
IGc2 172..237 CDD:197706 23/70 (33%)
IG_like 267..348 CDD:214653 21/84 (25%)
Ig 270..339 CDD:299845 19/72 (26%)
Dscam2NP_001261500.1 Ig 51..127 CDD:299845
Ig 138..>203 CDD:299845
I-set 238..327 CDD:254352
Ig 247..327 CDD:299845
I-set 332..418 CDD:254352
IGc2 344..407 CDD:197706
IG_like 432..517 CDD:214653
IGc2 436..507 CDD:197706
I-set 521..610 CDD:254352 8/40 (20%)
IGc2 533..597 CDD:197706 6/24 (25%)
Ig 630..699 CDD:143165 17/80 (21%)
IG_like 714..802 CDD:214653 28/89 (31%)
Ig 725..802 CDD:299845 26/78 (33%)
Ig 823..894 CDD:143165 20/74 (27%)
FN3 906..1006 CDD:238020 13/68 (19%)
FN3 1013..1111 CDD:238020
FN3 1119..1209 CDD:238020
FN3 1219..1313 CDD:238020
Ig 1336..1402 CDD:143165
FN3 1409..1498 CDD:238020
FN3 1515..1588 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.810

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