DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DIP-epsilon and CG17716

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_001286391.1	Gene:	CG17716 / 36521	FlyBaseID:	FBgn0000633	Length:	822	Species:	Drosophila melanogaster

Alignment Length:	428	Identity:	96/428 - (22%)
Similarity:	165/428 - (38%)	Gaps:	104/428 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 VKLACSVKNLGSYKVAWMHFEQSAILTVHNHVITRNPRISVTHDKHDKHRTWFLHINNVQEEDRG 133
            :||.|.| :|......|  ::...::    |.:.|..|  ||..:..|.....|.|.||..||.|
  Fly   254 IKLMCEV-DLDIATSMW--YKNGQVV----HAMDRTAR--VTDYRFIKEANGALTITNVMLEDDG 309

  Fly   134 RYMCQINTVTAKTQYGF-VKVVV-----PPN--IDD-ALTSSDII--VREGDNVTLRCKAK-GSP 186
            ::.|:.......|:... ||:||     ||.  ||. .|.:|::.  |:|...:.|.|.:: |:|
  Fly   310 KWQCEAENTRRYTENARPVKLVVLDRPKPPYLLIDSRRLDASNLFVPVKENSELNLACVSEGGNP 374

  Fly   187 EPTIKWK------RDDGNKIVINKTLEVHDLETDSLE---------------LERISRLHMGA-Y 229
            .||:.|:      .|...:.|..:.||:.:::.:.|:               |..:.|.|..| .
  Fly   375 RPTLTWEVLLSPGVDRHAQKVSAEVLELEEIKGEKLDKDGYKINSGAKSEARLPAVYRAHHNARI 439

  Fly   230 LCIASNGVPPSVSKR----IKVSVDFSPMVWIPHQL-VGIPI--GFNITLECFIEANPTSLNYWT 287
            ||:..:   |::..|    :.:.|.::|...|.... .|.|:  |..::|:|.:::||.|...|.
  Fly   440 LCVMEH---PTLKIRQNASLLLDVQYTPSFAISRTPGFGYPLREGIEVSLKCDVDSNPPSTPRWQ 501

  Fly   288 REN-DQMITESSKYKTETIPGHPSYKATMRLTITNVQSSDYGNYKCVAKNPRGDMDGNIKLYMS- 350
            ::: |..:       .:|..|.        |..|:::....|.|||.:::..... .:|..|:|
  Fly   502 KDDGDTPV-------PQTGDGF--------LNFTSIRREHSGWYKCTSRHLNFQY-SSIGYYLSV 550

  Fly   351 --------SPPTTQPPPTTTTLRRTTTTAAEIALDGYIN--------------TPLNG--NGIGI 391
                    |.|..|................|:.|.|.:.              .|::.  .|:|.
  Fly   551 RFDSVDVTSEPDDQDVSVAAASHNPNKGQLEVQLGGAVTLQCPQGSLGCWSHLDPISARLRGLGY 615

  Fly   392 VGEGPTNSVIASGKSSIKYLSNLNEIDKSKQKLTGSSP 429
            ....||      |:.|:|   ::...|....|..|.||
  Fly   616 GSSQPT------GQFSLK---DVMYQDAGMYKCVGQSP 644

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	23/86 (27%)
		Ig	69..139	CDD:143165	20/69 (29%)
		IG_like	165..249	CDD:214653	23/112 (21%)
		IGc2	172..237	CDD:197706	19/87 (22%)
		IG_like	267..348	CDD:214653	17/81 (21%)
		Ig	270..339	CDD:299845	15/69 (22%)
CG17716	NP_001286391.1	IG_like	244..332	CDD:214653	23/86 (27%)
		Ig	254..323	CDD:143165	20/77 (26%)
		Ig	359..452	CDD:299845	20/95 (21%)
		Ig_3	477..536	CDD:290638	17/73 (23%)
		IG_like	479..550	CDD:214653	18/86 (21%)
		IG_like	578..660	CDD:214653	16/76 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910