DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-epsilon and LRIT3

DIOPT Version :9

Sequence 1:NP_001137799.1 Gene:DIP-epsilon / 7354433 FlyBaseID:FBgn0259714 Length:467 Species:Drosophila melanogaster
Sequence 2:NP_940908.3 Gene:LRIT3 / 345193 HGNCID:24783 Length:679 Species:Homo sapiens


Alignment Length:254 Identity:55/254 - (21%)
Similarity:87/254 - (34%) Gaps:91/254 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly   194 RDDGNKIV-----------INKTLEVHDLETDSLELERISRLHMGAYLCIASN---GVPPS---- 240
            |.|||.:.           :.:||::|:.:..|:..|.:..|...|||.::||   .:||.    
Human   111 RLDGNSLAAFPWASLLDMPLLRTLDLHNNKITSVPNEALRYLKNLAYLDLSSNRLTTLPPDFLES 175

  Fly   241 ---------------------------------VSKRIKVSVDFSPMVWI---------PHQLVG 263
                                             :||.|::|....|.:.:         |.:|.|
Human   176 WTHLVSTPSGVLDLSPSRIILGLQDNPWFCDCHISKMIELSKVVDPAIVLLDPLMTCSEPERLTG 240

  Fly   264 I------------------------PIGFNITLECFIEANPTSLNYWTRENDQMITESSKYKTET 304
            |                        .:|.|:.|.|.....||....|||      ::||......
Human   241 ILFQRAELEHCLKPSVMTSATKIMSALGSNVLLRCDATGFPTPQITWTR------SDSSPVNYTV 299

  Fly   305 IPGHPSYKATMR-LTITNVQSSDYGNYKCVAKNPRGDMDGNIKLYMSSPPTTQPPPTTT 362
            |...|....... :::|.:.|.|.|:|||.|||..|..:..:.:.:....||..||.|:
Human   300 IQESPEEGVRWSIMSLTGISSKDAGDYKCKAKNLAGMSEAVVTVTVLGITTTPIPPDTS 358

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-epsilonNP_001137799.1 IG_like 59..155 CDD:214653
Ig 69..139 CDD:143165
IG_like 165..249 CDD:214653 20/105 (19%)
IGc2 172..237 CDD:197706 15/56 (27%)
IG_like 267..348 CDD:214653 24/81 (30%)
Ig 270..339 CDD:299845 21/69 (30%)
LRIT3NP_940908.3 LRR 1 56..79
leucine-rich repeat 59..82 CDD:275378
LRR_8 61..117 CDD:290566 4/5 (80%)
LRR 2 80..103
leucine-rich repeat 83..106 CDD:275378
LRR 3 104..128 4/16 (25%)
LRR_8 105..165 CDD:290566 15/53 (28%)
LRR_4 105..146 CDD:289563 8/34 (24%)
leucine-rich repeat 107..130 CDD:275378 4/18 (22%)
LRR 4 129..151 5/21 (24%)
LRR_4 131..170 CDD:289563 11/38 (29%)
leucine-rich repeat 131..154 CDD:275378 6/22 (27%)
LRR 5 152..175 8/22 (36%)
leucine-rich repeat 155..168 CDD:275378 5/12 (42%)
Ig 267..345 CDD:299845 24/83 (29%)
IG_like 267..345 CDD:214653 24/83 (29%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 351..375 4/8 (50%)
FN3 486..550 CDD:214495
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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