DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DIP-epsilon and bdl

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_608822.1	Gene:	bdl / 33635	FlyBaseID:	FBgn0028482	Length:	719	Species:	Drosophila melanogaster

Alignment Length:	416	Identity:	91/416 - (21%)
Similarity:	147/416 - (35%)	Gaps:	98/416 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 NITVPAGRNVKLACSVKNLGS----YKVAWMH--------FEQ----SAILTVHNHVITRNP--- 105
            |:....|.:|...|.:.....    |.|.|..        :||    |.:.....|::..:|
  Fly    42 NLEAKVGSHVVFNCYIDFPFDAPIPYLVHWTKDNKKIFTWYEQETSTSELFNGRLHLVENHPEFG 106

  Fly   106 RISVTHDKHDKHRTWFLHINNVQEEDRGRYMCQI----------NTVTA---KTQYGFVKVVVPP 157
            |.||             ::..::|.|:|.|.||:          |..||   ..|.|.: :.:||
  Fly   107 RASV-------------NLTAIRESDQGWYHCQVSFPNRSPSVRNNGTAYHLAVQGGSL-IRIPP 157

  Fly   158 NIDDALTSSDIIVREGDNVTLRCKAKGSPEPTIKWKRDDGNKIVINKTLEVHDL-------ETDS 215
                    .:..:|||......|..|........|.:|.   :::.   ||.||       ...|
  Fly   158 --------VNQTIREGQTAFFHCVMKHPENSQASWYKDG---VLLQ---EVQDLVRRFYMGPDGS 208

  Fly   216 LELERISRLHMGAYLCIASNGVPPSVSKRIKVSVDF-SPMVWIPHQLVGIPIGFNITLECFIEAN 279
            |.::......:|.|.|...|......:.:..:::.: :.:::.|.: |.:|.|....|:|...||
  Fly   209 LSIDPTMMSDLGEYECKVRNSDGELQTAKAFLNIQYKAKVIYAPPE-VFLPYGQPAVLDCHFRAN 272

  Fly   280 PTSLNY-WTRENDQMITESSKYKTETIPGHPSYKATMRLTITNVQSSDYGNYKCVAKNPRGDMDG 343
            |...|. |  |.|.::.:|     ..:|| ..||....|....|..:..|:|.|...|..| .||
  Fly   273 PPLKNLRW--EKDGLLFDS-----YNVPG-VFYKMNGSLFFAKVDENHAGSYTCTPYNDLG-TDG 328

  Fly   344 N---IKLYMSSPPTTQPPPTTTTLRRTTTTAAEI---ALDGYINT------------PLNGNGIG 390
            .   |.:.:..||.....|....::: ...|||:   |:|...|.            ||..:...
  Fly   329 PSPVISVIVLRPPIFSVTPKAIYIQK-LGEAAELPCEAIDRDGNNRPSIIWGRKDGQPLPADRFS 392

  Fly   391 IVGEGPTNSVIASGKSSIKYLSNLNE 416
            :.|...|.:.:..|...|...|..||
  Fly   393 LSGGNLTITGLVEGDRGIYECSATNE 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	26/126 (21%)
		Ig	69..139	CDD:143165	18/88 (20%)
		IG_like	165..249	CDD:214653	17/90 (19%)
		IGc2	172..237	CDD:197706	16/71 (23%)
		IG_like	267..348	CDD:214653	25/84 (30%)
		Ig	270..339	CDD:299845	20/69 (29%)
bdl	NP_608822.1	IG_like	42..128	CDD:214653	21/98 (21%)
		Ig	43..131	CDD:299845	20/100 (20%)
		I-set	153..242	CDD:254352	19/102 (19%)
		Ig	157..242	CDD:299845	18/98 (18%)
		Ig_2	252..337	CDD:290606	28/94 (30%)
		IG_like	260..327	CDD:214653	22/75 (29%)
		I-set	341..428	CDD:254352	17/79 (22%)
		IGc2	356..419	CDD:197706	15/63 (24%)
		FN3	435..524	CDD:238020
		FN3	554..636	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810