DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-epsilon and Sdk1

DIOPT Version :9

Sequence 1:NP_001137799.1 Gene:DIP-epsilon / 7354433 FlyBaseID:FBgn0259714 Length:467 Species:Drosophila melanogaster
Sequence 2:NP_808547.3 Gene:Sdk1 / 330222 MGIID:2444413 Length:2193 Species:Mus musculus


Alignment Length:392 Identity:96/392 - (24%)
Similarity:148/392 - (37%) Gaps:79/392 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    27 STDTGSEGNAGNVGGSTLNNV-------ISEDPEFT---------DVIENITVPAGRNVKLACSV 75
            |.|||.......:.|||....       |.|.|.||         :|.|.:.:|        |..
Mouse   336 SADTGMYVCEATLRGSTFEPARARAFLSIIEPPYFTAEPESRILGEVEETMDIP--------CRA 392

  Fly    76 KNLGSYKVAWMHFEQSAILTVHNHVITRNPRISVTHDKHDKHRTWFLHINNVQEEDRGRYMCQIN 140
            ..:....:.|  ::.:..|:.     .:|||..|.       .:..|||..:..||.|.:.|..:
Mouse   393 MGVPLPTLQW--YKDAVPLSK-----LQNPRYKVL-------PSGGLHIQKLSPEDSGIFQCFAS 443

  Fly   141 TVTAKTQ-YGFVKVVVPPNIDDALTSS--DIIVREGDNVTLRCKAKGSPEPTIKWKRDDGNKIVI 202
            ....:.| :.::.|.   ||..|.|..  |..|.:|....|||:..|:|:|.|.|||  ||.|:.
Mouse   444 NEGGEVQTHTYLDVT---NIAPAFTQRPVDTTVTDGMTAVLRCEVSGAPKPAITWKR--GNHILA 503

  Fly   203 NKTLEVHD---LETDSLELERISRLHMGAYLCIASNGVPPSVSKRIKVSVDFSPM--VWIPHQLV 262
            :.::.:..   ||:..|.:..:.....|.|.|.|:|         .:.||:.|.|  ||....:|
Mouse   504 SGSVRIPRFMLLESGGLRIAPVFIQDAGNYTCYAAN---------TEASVNASAMLTVWNRTSIV 559

  Fly   263 GIP------IGFNITLECFIEANP-TSLNYWTRENDQMITESSKYKTETIPGHPSYKATMRLTIT 320
            ..|      .|...||.|....:| |||.|..::::.:||.||..:...       :....|.|:
Mouse   560 HPPEDRVVIKGTTATLCCGATHDPRTSLRYVWKKDNVVITASSSSRIVV-------EKDGSLVIS 617

  Fly   321 NVQSSDYGNYKCVAKNPRGDMDGNIKLYMSSPPTTQPPPTTTTLRRTTTTAAEIALDGYINTPLN 385
            ...|.|.|:|.|...:..|......:|.:...|   .||.......:...:..:.|...  .|.:
Mouse   618 QTWSGDIGDYTCEIISEGGSDSRTARLEVIELP---HPPQNLLASLSPARSHSVTLSWV--RPFD 677

  Fly   386 GN 387
            ||
Mouse   678 GN 679

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-epsilonNP_001137799.1 IG_like 59..155 CDD:214653 18/96 (19%)
Ig 69..139 CDD:143165 14/69 (20%)
IG_like 165..249 CDD:214653 24/88 (27%)
IGc2 172..237 CDD:197706 22/67 (33%)
IG_like 267..348 CDD:214653 21/81 (26%)
Ig 270..339 CDD:299845 19/69 (28%)
Sdk1NP_808547.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..56
Ig_2 94..169 CDD:290606
IG_like 100..169 CDD:214653
IG_like 183..263 CDD:214653
Ig 197..247 CDD:299845
IG_like 281..357 CDD:214653 7/20 (35%)
IGc2 294..347 CDD:197706 4/10 (40%)
I-set 368..457 CDD:254352 21/110 (19%)
Ig 388..454 CDD:143165 16/87 (18%)
I-set 462..552 CDD:254352 30/100 (30%)
Ig 476..552 CDD:299845 26/86 (30%)
I-set 557..646 CDD:254352 24/95 (25%)
Ig 562..646 CDD:299845 23/90 (26%)
FN3 650..741 CDD:238020 7/35 (20%)
fn3 753..839 CDD:278470
FN3 854..949 CDD:238020
FN3 954..1036 CDD:238020
FN3 1052..1148 CDD:238020
FN3 1158..1253 CDD:238020
FN3 1261..1349 CDD:238020
FN3 1360..1453 CDD:238020
FN3 1459..1554 CDD:238020
FN3 1562..1676 CDD:238020
FN3 1686..1779 CDD:238020
FN3 1784..1865 CDD:238020
FN3 1885..1978 CDD:238020
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 2057..2080
PDZ-binding. /evidence=ECO:0000250|UniProtKB:Q6V4S5 2187..2193
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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