DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-epsilon and AgaP_AGAP009245

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_553184.3	Gene:	AgaP_AGAP009245 / 3291935	VectorBaseID:	AGAP009245	Length:	203	Species:	Anopheles gambiae

Alignment Length:	200	Identity:	50/200 - (25%)
Similarity:	73/200 - (36%)	Gaps:	41/200 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 TLNNVISEDPEF-TDVIENITVPAGRNVKLACSVKNLGSYKVAWMHFEQSAILTVHNHVITRNPR 106
            |..:.:...|.| .....|:|...|....|.|.|:|||:..|:|:......:|||.....|.:.|
Mosquito    31 TAKSPLDRGPYFDISASRNVTALVGNTAYLNCRVRNLGNRTVSWIRHRDLHLLTVGKATYTSDQR 95

  Fly   107 ISVTHDKHDKHRTWFLHINNVQEEDRGRYMCQINTVTAKTQYGFVKVVVPPNIDDALTSSDIIVR 171
            ....|  :.:...|.|.:...|:.|.|.|.|||:|             .||
Mosquito    96 YQSVH--NPQLDDWSLKVLYPQQRDSGVYECQIST-------------TPP-------------- 131

  Fly   172 EGDNVTLRCKAKGSPEPTIKWKRDDGNKIVINKTLEVHDLETDSLELERISRLHMGAYLCIASNG 236
            .|.::||..:        |.:....|...||.   |..|:.|..|.::|......|.|.|:.|..
Mosquito   132 VGYSMTLSVE--------INYDSPRGGVSVIT---EKGDITTSYLLIQRARSTDSGKYTCLPSMA 185

  Fly   237 VPPSV 241
            .|.:|
Mosquito   186 NPTTV 190

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	27/95 (28%)
		Ig	69..139	CDD:143165	21/69 (30%)
		IG_like	165..249	CDD:214653	17/76 (22%)
		IGc2	172..237	CDD:197706	16/64 (25%)
		IG_like	267..348	CDD:214653
		Ig	270..339	CDD:299845
AgaP_AGAP009245	XP_553184.3	Ig	47..140	CDD:299845	32/121 (26%)
		IG_like	47..140	CDD:214653	32/121 (26%)
		IG_like	127..>180	CDD:214653	17/90 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810