DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-epsilon and AgaP_AGAP006350

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_557013.3	Gene:	AgaP_AGAP006350 / 3290147	VectorBaseID:	AGAP006350	Length:	319	Species:	Anopheles gambiae

Alignment Length:	219	Identity:	50/219 - (22%)
Similarity:	85/219 - (38%)	Gaps:	38/219 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 DPEF-TDVIENITVPAGRNVKLACSVKNLGSYKVAWMHFEQSAILTVHNHVITRNPRISVTHDKH 114
            :|:| ..|..|:||..|....|.|.|:||..|.::|:......||.::....|.:.|....:  :
Mosquito    38 EPQFDLSVSRNVTVREGETAFLTCRVENLAKYSISWVRHHDLHILAINADTFTSDERFQALY--N 100

  Fly   115 DKHRTWFLHINNVQEEDRGRYMCQINTVTAKT--------QYGFVKVVVPPNIDDALTSSDIIVR 171
            |:...|.|.:...:.:|...|.|||:|:..|:        .|.|:....     ..|..:.:...
Mosquito   101 DQTAEWTLKLRRTRRKDTDIYECQISTMPVKSLQLYLIVLDYHFLTTTT-----QILEGTIVYGY 160

  Fly   172 EGDNVTLRCKAKGS----PEPTIKWKRDDGNKIVINKTLEVHDLETDSLELERISRLHM------ 226
            :|.||.|.|....:    |...:.:.:.|   ||..::|.    :.....|..|:..|:
Mosquito   161 KGQNVNLTCIVNHNYDRRPSHIVWYHQKD---IVAYESLR----KRGRSSLNSITSYHLIRSAEF 218

  Fly   227 ---GAYLCIASNGVPPSVSKRIKV 247
               |.|.|...  :.||.|..:.:
Mosquito   219 DDAGNYTCAPE--LYPSASTIVHI 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	27/103 (26%)
		Ig	69..139	CDD:143165	17/69 (25%)
		IG_like	165..249	CDD:214653	19/96 (20%)
		IGc2	172..237	CDD:197706	16/77 (21%)
		IG_like	267..348	CDD:214653
		Ig	270..339	CDD:299845
AgaP_AGAP006350	XP_557013.3	Ig	45..139	CDD:299845	26/95 (27%)
		IG_like	46..126	CDD:214653	22/81 (27%)
		IG_like	157..227	CDD:214653	15/76 (20%)
		Ig	165..>226	CDD:143165	13/67 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810