DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-epsilon and dpr8

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_001285239.1	Gene:	dpr8 / 32387	FlyBaseID:	FBgn0052600	Length:	344	Species:	Drosophila melanogaster

Alignment Length:	250	Identity:	72/250 - (28%)
Similarity:	106/250 - (42%)	Gaps:	32/250 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LYVGLGCLIA-----SSVALSTDTGSEGNAGNVGGSTLNNVISEDPEFTDVIENITVPAGRNVKL 71
            :::|:.||:|     :|....||...:......||.|.:..|.         .|||...|:.|||
  Fly     7 IFLGILCLLAGCTDGASKRFFTDFLQDLPTPGTGGPTFDTTIG---------TNITGLVGKTVKL 62

  Fly    72 ACSVKNLGSYKVAWMHFEQSAILTVHNHVITRNPRISVTHDKHDKHRTWFLHINNVQEEDRGRYM 136
            .|.|||||:..|:|:......:|||..:..|.:.|....|..|.:  .|.|.|...|.:|.|.|.
  Fly    63 TCRVKNLGNRTVSWVRHRDIHLLTVGRYTYTSDQRFEAMHSPHAE--DWTLRIRYAQRKDSGIYE 125

  Fly   137 CQINTVTAKTQYGFVKVVVPPNIDDALTSSDIIVREGDNVTLRCKAKGSPE--PTIKWKRDDGNK 199
            |||:|........::.:|.|  :.|.:...::.:..|..:.|.|..|.:||  ||:.|..   |:
  Fly   126 CQISTTPPIGHSVYLNIVEP--VTDIIGGPELHINRGSTINLTCIVKFAPEPPPTVIWSH---NR 185

  Fly   200 IVIN---------KTLEVHDLETDSLELERISRLHMGAYLCIASNGVPPSVSKRI 245
            .:||         ...|...|.|..|.:::......|.|.|..||..|.||...|
  Fly   186 EIINFDSPRGGISLVTEKGVLTTSRLLVQKAITQDSGLYTCTPSNANPTSVRVHI 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	33/95 (35%)
		Ig	69..139	CDD:143165	26/69 (38%)
		IG_like	165..249	CDD:214653	24/91 (26%)
		IGc2	172..237	CDD:197706	21/75 (28%)
		IG_like	267..348	CDD:214653
		Ig	270..339	CDD:299845
dpr8	NP_001285239.1	IG_like	51..131	CDD:214653	32/81 (40%)
		V-set	52..143	CDD:284989	32/92 (35%)
		IG_like	153..238	CDD:214653	24/87 (28%)
		ig	153..232	CDD:278476	21/81 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	46	1.000	Domainoid score	I11916
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.810