DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment DIP-epsilon and Prtg

DIOPT Version :9

Sequence 1:NP_001137799.1 Gene:DIP-epsilon / 7354433 FlyBaseID:FBgn0259714 Length:467 Species:Drosophila melanogaster
Sequence 2:NP_001032740.2 Gene:Prtg / 315806 RGDID:1307157 Length:1193 Species:Rattus norvegicus


Alignment Length:310 Identity:66/310 - (21%)
Similarity:116/310 - (37%) Gaps:47/310 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    63 VPAGRNVKLACSVKNLGSYKVAWMHFEQSAILTVHNHVITRNPRISVTHDKHDKHRTWFLHINNV 127
            ||.|...:.:|.:.:.....:.| .|.::|:....:..:|..|             :..|.|.:.
  Rat   140 VPEGGVARFSCKISSTPPAVITW-EFNRTALPMTMDSRVTALP-------------SGVLQIYDA 190

  Fly   128 QEEDRGRYMCQINTVTAKTQYGFVKVVVPPNIDDALTSSDIIVREGDNVT--------LRCKAKG 184
            ..||.|:|.|...|...|.:.....:.:.|..:........|:....|||        |.|.|.|
  Rat   191 GPEDAGKYRCVAATHAHKRKSMEASLTI
VPANETRSFYMPTIIASPQNVTASLHQTVVLECMATG 255

  Fly   185 SPEPTIKWKRDDGNKIVINKTLEVHD---LETDSLELERISRLHMGAYLCIASNGVPPSVSKRIK 246
            .|:|.|.|.|.|      :|:::|.:   |...:|.:..:...|.|.|:|.|:.....:.:..:.
  Rat   256 YPKPIISWSRLD------HKSIDVFNTRVLGNGNLIISDVKLQHAGVYVCRATTPGTRNFTVAMA 314

  Fly   247 VSVDFSPMVWI--PHQLVGIPIGFNITLECFIEANPTSLNYWTRENDQMITESSKYKTETIPGHP 309
            .....:|..::  |..|.. |........|..|..|:....|.: |.:.|..:.:.|        
  Rat   315 TLTVLAPPSFVEWPESLTR-PRAGTARFVCQAEGIPSPKMSWLK-NGRRIHSNGRIK-------- 369

  Fly   310 SYKATMRLTITNVQSSDYGNYKCVAKNPRGDMDGNIKL--YMSSPPTTQP 357
            .|.:  :|.|..:...|...|:|:|:|.:|.:....:|  .||....:.|
  Rat   370 MYNS--KLVINQIIPEDDAIYQCMAENSQGSVLSRARLTVVMSEDRPSAP 417

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-epsilonNP_001137799.1 IG_like 59..155 CDD:214653 18/91 (20%)
Ig 69..139 CDD:143165 13/69 (19%)
IG_like 165..249 CDD:214653 23/94 (24%)
IGc2 172..237 CDD:197706 22/75 (29%)
IG_like 267..348 CDD:214653 17/82 (21%)
Ig 270..339 CDD:299845 15/68 (22%)
PrtgNP_001032740.2 Ig 32..124 CDD:416386
Ig strand A 32..35 CDD:409353
Ig strand A' 38..44 CDD:409353
Ig strand B 48..58 CDD:409353
Ig strand C 62..68 CDD:409353
Ig strand C' 70..73 CDD:409353
Ig strand D 78..83 CDD:409353
Ig strand E 85..91 CDD:409353
Ig strand F 103..110 CDD:409353
Ig strand G 114..124 CDD:409353
Ig 131..218 CDD:416386 18/91 (20%)
Ig strand B 146..150 CDD:409353 0/3 (0%)
Ig strand C 159..163 CDD:409353 1/4 (25%)
Ig strand E 183..187 CDD:409353 1/3 (33%)
Ig strand F 197..202 CDD:409353 2/4 (50%)
Ig strand G 211..214 CDD:409353 0/2 (0%)
Ig_3 230..302 CDD:404760 22/77 (29%)
Ig strand B 247..251 CDD:409353 1/3 (33%)
Ig strand C 260..264 CDD:409353 1/3 (33%)
Ig strand E 282..286 CDD:409353 1/3 (33%)
Ig strand F 296..301 CDD:409353 2/4 (50%)
I-set 322..407 CDD:400151 20/96 (21%)
Ig strand C 352..357 CDD:409353 1/4 (25%)
Ig strand C' 359..362 CDD:409353 0/2 (0%)
Ig strand D 367..371 CDD:409353 1/11 (9%)
Ig strand E 373..378 CDD:409353 1/6 (17%)
Ig strand F 387..394 CDD:409353 3/6 (50%)
Ig strand G 398..407 CDD:409353 1/8 (13%)
FN3 414..507 CDD:238020 1/4 (25%)
FN3 512..605 CDD:238020
fn3 619..694 CDD:394996
FN3 721..809 CDD:238020
FN3 816..906 CDD:238020
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 974..1018
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1078..1193
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR12231
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

Return to query results.
Submit another query.