DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DIP-epsilon and Fas2

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_001284854.1	Gene:	Fas2 / 31364	FlyBaseID:	FBgn0000635	Length:	885	Species:	Drosophila melanogaster

Alignment Length:	383	Identity:	91/383 - (23%)
Similarity:	153/383 - (39%)	Gaps:	67/383 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 FTDVIENITVPAGRNVKLACSVKNLGSYKVAWMHFEQSAILTVHNHVITRN-PRISVTHDKHDKH 117
            :|:..||.....|::..:.|.||...:..:.|:                || ..|..|:||:...
  Fly   140 WTNAPENQYPTLGQDYVVMCEVKADPNPTIDWL----------------RNGDPIRTTNDKYVVQ 188

  Fly   118 RTWFLHINNVQEEDRGRYMCQ---INTVTAKTQYGFVKVVVPPNIDDALTSSDIIVREGDNVTLR 179
            ....| |.||||.|.|.|.|:   |.|.....:...|:|.:.|.|....|:.:.:  ||......
  Fly   189 TNGLL-IRNVQESDEGIYTCRAAVIETGELLERTIRVEVFIQPEIISLPTNLEAV--EGKPFAAN 250

  Fly   180 CKAKGSPEPTIKWKRD-------DGNKIVINKTLEVHDLETDSLELERISRLHMGAYLCIASN-- 235
            |.|:|.|.|.|.|.||       ..::..:|.       :|..:.:..:|:...|.|.|:|.|
  Fly   251 CTARGKPVPEISWIRDATQLNVATADRFQVNP-------QTGLVTISSVSQDDYGTYTCLAKNRA 308

  Fly   236 GVPPSVSKRIKVSVDFSPMVWIPHQLVGIPIGFNITLECFIEANPT---SLNYWTRENDQMITES 297
            ||   |.::.|::|...|.::..:.:.|.... .|.:.|..:..|.   :...|..:.:  .|..
  Fly   309 GV---VDQKTKLNVLVRPQIYELYNVTGARTK-EIAITCRAKGRPAPAITFRRWGTQEE--YTNG 367

  Fly   298 SKYKTETIPGHPSY-----KATMRLTITNVQSSDYGNYKCVAKNPRGD--MDGNIKLYMS---SP 352
            .:.....|...|::     ::|..|.|:|.:.||.|.|:|:|:|...|  ..|:|.:..:   |.
  Fly   368 QQDDDPRIILEPNFDEERGESTGTLRISNAERSDDGLYQCIARNKGADAYKTGHITVEFAPDFSH 432

  Fly   353 PTTQPPPTTTTLRRTTTTAAEIAL-DGYINTPLNG--------NGIGIVGEGPTNSVI 401
            ....||..:...|:...:...:.: :..|....||        ..:.|||.||.:.:|
  Fly   433 MKELPPVFSWEQRKANLSCLAMGIPNATIEWHWNGRKIKDLYDTNLKIVGTGPRSDLI 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	27/99 (27%)
		Ig	69..139	CDD:143165	20/73 (27%)
		IG_like	165..249	CDD:214653	23/92 (25%)
		IGc2	172..237	CDD:197706	19/73 (26%)
		IG_like	267..348	CDD:214653	21/90 (23%)
		Ig	270..339	CDD:299845	18/76 (24%)
Fas2	NP_001284854.1	IG_like	39..133	CDD:214653
		IG_like	144..226	CDD:214653	26/98 (27%)
		IGc2	152..209	CDD:197706	21/73 (29%)
		I-set	230..319	CDD:254352	26/100 (26%)
		IGc2	243..309	CDD:197706	19/72 (26%)
		IG_like	330..424	CDD:214653	22/96 (23%)
		IGc2	339..412	CDD:197706	17/74 (23%)
		Ig	447..518	CDD:143165	9/44 (20%)
		fn3	534..611	CDD:278470
		FN3	640..735	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810