DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-epsilon and Lsamp

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_030104997.1	Gene:	Lsamp / 268890	MGIID:	1261760	Length:	392	Species:	Mus musculus

Alignment Length:	308	Identity:	98/308 - (31%)
Similarity:	147/308 - (47%)	Gaps:	26/308 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 EFTDVIENITVPAGRNVKLACSVKNLGSYKVAWMHFEQSAILTVHNHVITRNPRISVTHDKHDKH 117
            :|....:||||..|....|.|.|::..| ||||::  :|.|:...:...:.:||:.:    ..:|
Mouse    64 DFNRGTDNITVRQGDTAILRCVVEDKNS-KVAWLN--RSGIIFAGHDKWSLDPRVEL----EKRH 121

  Fly   118 R-TWFLHINNVQEEDRGRYMCQINTV-TAKTQYGFVKVVVPPNIDDALTSSDIIVREGDNVTLRC 180
            . .:.|.|..|...|.|.|.|.:.|. ..||...::.|.|||.|.:  .|||:.|.||.||||.|
Mouse   122 ALEYSLRIQKVDVYDEGSYTCSVQTQHEPKTSQVYLIVQVPPKISN--ISSDVTVNEGSNVTLVC 184

  Fly   181 KAKGSPEPTIKWKRDDGNKIVINKTLEVHDLETDSLELERISRLHMGAYLCIASNGVPPSVSKRI 245
            .|.|.|||.|.|:    :...:.:..|.   |.:.||:..|:|...|.|.|.|:|.|..:..|::
Mouse   185 MANGRPEPVITWR----HLTPLGREFEG---EEEYLEILGITREQSGKYECKAANEVSSADVKQV 242

  Fly   246 KVSVDFSPMVWIPHQLVGIPIGFNITLECFIEANPTSLNYWTRENDQMITESSKYKTETIPGHPS 310
            ||:|::.|.: ...:......|...:|:|...|.|.....|.|: |..|..::..:.::..|..|
Mouse   243 KVTVNYPPTI-TESKSNEATTGRQASLKCEASAVPAPDFEWYRD-DTRINSANGLEIKSTEGQSS 305

  Fly   311 YKATMRLTITNVQSSDYGNYKCVAKNPRGDMDGNIKLYMSSPPTTQPP 358
                  ||:|||....||||.|||.|..|..:.::.|:....||...|
Mouse   306 ------LTVTNVTEEHYGNYTCVAANKLGVTNASLVLFKRVLPTVPHP 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	29/97 (30%)
		Ig	69..139	CDD:143165	20/70 (29%)
		IG_like	165..249	CDD:214653	33/83 (40%)
		IGc2	172..237	CDD:197706	25/64 (39%)
		IG_like	267..348	CDD:214653	25/80 (31%)
		Ig	270..339	CDD:299845	23/68 (34%)
Lsamp	XP_030104997.1	Ig	69..159	CDD:386229	28/96 (29%)
		Ig_3	163..232	CDD:372822	30/77 (39%)
		Ig_3	250..325	CDD:372822	24/82 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833576
Domainoid	1	1.000	45	1.000	Domainoid score	I12107
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	142	1.000	Inparanoid score	I4449
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	1	1.000	-	-		mtm8732
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3058
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.930