DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-epsilon and LRIT1

DIOPT Version :9

Sequence 1:NP_001137799.1 Gene:DIP-epsilon / 7354433 FlyBaseID:FBgn0259714 Length:467 Species:Drosophila melanogaster
Sequence 2:NP_056428.1 Gene:LRIT1 / 26103 HGNCID:23404 Length:623 Species:Homo sapiens


Alignment Length:296 Identity:57/296 - (19%)
Similarity:88/296 - (29%) Gaps:110/296 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly   173 GDNVTLRCKAKGSPEPTIKWKRDDGNKIVINKTLEVH-DLETDS-----LELERISRLHMGAYLC 231
            |....|||.|.|.|.|.:.|:|.:|..  :|.|  || ::.:|.     |.|..:|.|..|.|:|
Human   268 GGTALLRCGATGVPGPEMSWRRANGRP--LNGT--VHQEVSSDGTSWTLLGLPAVSHLDSGDYIC 328

  Fly   232 IASNGVPPSVSKRIKVSVDFSPMVWIPHQLVGIPIGFNITLECFIEANPTSLNY-------WTRE 289
            .|.|.:..|                            ...:...:...|||..:       |.|.
Human   329 QAKNFLGAS----------------------------ETVISLIV
TEPPTSTEHSGSPGALWART 365

  Fly   290 NDQMITESSKYKTETIPGH-------------PSYKATM-RLTITNVQSSDYGNYKCVAKNPR-- 338
            ...  .|::.|..:.:..|             ||..:|. .||:.:.|....|........|.  
Human   366 GGG--GEAAAYNNKLVARHVPQIPKPAVLATGPSVPSTKEELTLEHFQMDALGELSDGRAGPSEA 428

  Fly   339 ---------GDMDGNIKLYMSSPPTTQPPPTTTTLRRTTTTAAEIALDGYINTPLNGNGIGIVGE 394
                     ||...::.|...:|            :...|||..:.             ..:.|:
Human   429 RMVRSVKVVGDTYHSVSLVWKAP------------QAKNTTAFSVL-------------YAVFGQ 468

  Fly   395 GPTNSVIASGKSSIKYLSNLNEIDKSKQKLTGSSPK 430
            .....||.             :..|::..:||..||
Human   469 HSMRRVIV-------------QPGKTRVTITGLLPK 491

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-epsilonNP_001137799.1 IG_like 59..155 CDD:214653
Ig 69..139 CDD:143165
IG_like 165..249 CDD:214653 26/81 (32%)
IGc2 172..237 CDD:197706 25/69 (36%)
IG_like 267..348 CDD:214653 18/112 (16%)
Ig 270..339 CDD:299845 16/100 (16%)
LRIT1NP_056428.1 LRR 1 60..81
leucine-rich repeat 61..84 CDD:275378
LRR_8 63..143 CDD:290566
LRR 2 84..105
leucine-rich repeat 85..132 CDD:275378
LRR 3 108..129
LRR_8 131..202 CDD:290566
LRR_4 131..171 CDD:289563
LRR 4 132..153
leucine-rich repeat 133..156 CDD:275378
LRR 5 156..177
leucine-rich repeat 157..180 CDD:275378
leucine-rich repeat 181..205 CDD:275378
TPKR_C2 201..>240 CDD:301599
Ig 267..345 CDD:299845 26/108 (24%)
IG_like 267..345 CDD:214653 26/108 (24%)
FN3 431..498 CDD:214495 15/99 (15%)
LRR 6. /evidence=ECO:0000305 571..594
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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