Protein Alignment DIP-epsilon and NEGR1

DIOPT Version :9

• Sequence 1: NP_001137799.1
• Gene: DIP-epsilon / 7354433
• FlyBaseID: FBgn0259714
• Length: 467
• Species: Drosophila melanogaster
• Sequence 2: NP_776169.2
• Gene: NEGR1 / 257194
• HGNCID: 17302
• Length: 354
• Species: Homo sapiens
• Alignment Length: 319
• Identity: 94/319 - (29%)
• Similarity: 146/319 - (45%)
• Gaps: 67/319 - (21%)

  Fly    58 IENITVPAGRNVKLACSVKNLGSYKVAWMHFEQSAILTVHNHVITRNPRISV-THDKHDKHRTWF 121
            ::|:.|..|....|.|.::: |:.|.||::  :|:|:.......:.:||:|: |.:|.|    :.
Human    45 VDNMMVRKGDTAVLRCYLED-GASKGAWLN--RSSIIFAGGDKWSVDPRVSISTLNKRD----YS 102

  Fly   122 LHINNVQEEDRGRYMCQINTV-TAKTQYGFVKVVVPPNIDDALTSSDIIVREGDNVTLRCKAKGS 185
            |.|.||...|.|.|.|.:.|. |.:|....:.|.|||.|.|  .|:|:.|.||.||||.|.|.|.
Human   103 LQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYD--ISNDMTVNEGTNVTLTCLATGK 165

  Fly   186 PEPTIKWKRDDGNKIVINKTLEVHDLETDSLELERISRLHMGAYLCIASNGVP-PSVSKRIKVSV 249
            |||:|.|:.       |:.:.:..: ....|::..|:|...|.|.|.|.|.|. |.| :::||.|
Human   166 PEPSISWRH-------ISPSAKPFE-NGQYLDIYGITRDQAGEYECSAENDVSFPDV-RKVKVVV 221

  Fly   250 DFSPMV--------------WIPHQLVGIPIGFNITLECFIEANPTSLNYWTRE----NDQMITE 296
            :|:|.:              .|..:..|:|              |.:..::..|    |.|....
Human   222 NFAPTIQEIKSGTVTPGRSGLIRCEGAGVP--------------PPAFEWYKGEKKLFNGQQGII 272

  Fly   297 SSKYKTETIPGHPSYKATMRLTITNVQSSDYGNYKCVAKNPRGDMDGNIKLYMSSPPTT 355
            ...:.|.:|           ||:|||....:|||.|||.|..|..:.::.|   :||:|
Human   273 IQNFSTRSI-----------LTVTNVTQEHFGNYTCVAANKLGTTNASLPL---NPPST 317

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	29/97 (30%)
		Ig	69..139	CDD:143165	22/70 (31%)
		IG_like	165..249	CDD:214653	31/84 (37%)
		IGc2	172..237	CDD:197706	23/64 (36%)
		IG_like	267..348	CDD:214653	19/84 (23%)
		Ig	270..339	CDD:299845	18/72 (25%)
NEGR1	NP_776169.2	IG	47..135	CDD:214652	28/94 (30%)
		IGc2	152..210	CDD:197706	23/65 (35%)
		Ig_3	225..301	CDD:372822	21/100 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143439
Domainoid	1	1.000	45	1.000	Domainoid score	I12195
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	1	1.000	-	-		mtm8497
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.750