DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-epsilon and Pvr

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_058772.2	Gene:	Pvr / 25066	RGDID:	3813	Length:	412	Species:	Rattus norvegicus

Alignment Length:	349	Identity:	77/349 - (22%)
Similarity:	120/349 - (34%)	Gaps:	81/349 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 VIENITVPAGRNVKLACSV---KNLGSYKVAWMHFEQSAILTVHNHVITRNPRISVTHDK----- 113
            |:.|.|...|.:..|.||:   .|:...::.||..:...          .:|.::|.|.|
  Rat    39 VLSNSTGFLGGSTVLHCSLASKDNVTITQLTWMKRDPDG----------SHPSVAVFHPKKGPSI 93

  Fly   114 HDKHRTWF-------------LHINNVQEEDRGRYMCQINT--VTAKTQYGFVKVVV-PPNIDDA 162
            .|..|..|             |.|:|::.||.|.|.|||.|  ..:|:...::||.. |.|..:|
  Rat    94 SDPERVKFLVAKVYEDLRNASLAISNLRVEDEGIYECQIATFPTGSKSANVWLKVFARPKNTAEA 158

  Fly   163 LTSSDIIVREGDNVTLRCKAKGSPEPTIKWKRD--------------DGNKIVINKTLEVHDLET 213
            |..|..::.:  :|.....|.|.|...|.|..:              .|...||:....|...:.
  Rat   159 LEPSPTLMPQ--DVAKCISADGHPPGRITWSSNVNGSYREMKETGSQPGTTTVISYLSMVPSSQA 221

  Fly   214 DSLEL----ERISRLHMGAYLCIASNGVPPSVSKRIKVSVDFSPMVWIPHQLVGIPIGFNITLEC 274
            |...:    |..|.........|.|...||      :||:......|    .:|:.   |:.|.|
  Rat   222 DGTNITCTVEHESFQEPDQQPLILSLPYPP------EVSISGYEGNW----YIGLT---NVNLTC 273

  Fly   275 FIEANPTSLNY-WTRENDQMITESSKYKTETIPGHPSYKAT-MRLTITNVQSSDYGNYKCVAKNP 337
            ...:.|...|| |:.            .|..:|....::.. ..|.|:.|...:...:.|.|.|.
  Rat   274 EARSKPPPTNYSWST------------ATGPLPNSTHFQENGSHLLISTVDDLNNTIFVCKAINA 326

  Fly   338 RGDMDGNIKLYMSSPPTTQPPPTT 361
            .|...|.:.:.:.......||.|:
  Rat   327 LGSGQGQVTILVKEASEILPPKTS 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	30/118 (25%)
		Ig	69..139	CDD:143165	21/90 (23%)
		IG_like	165..249	CDD:214653	19/101 (19%)
		IGc2	172..237	CDD:197706	15/82 (18%)
		IG_like	267..348	CDD:214653	17/82 (21%)
		Ig	270..339	CDD:299845	14/70 (20%)
Pvr	NP_058772.2	IG_like	41..148	CDD:214653	28/116 (24%)
		Ig1_PVR_like	49..148	CDD:143195	25/108 (23%)
		Ig	152..246	CDD:299845	19/95 (20%)
		IG_like	268..338	CDD:214653	17/81 (21%)
		Ig	<269..342	CDD:299845	16/84 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910