DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-epsilon and Ncam1

DIOPT Version :9

Sequence 1:NP_001137799.1 Gene:DIP-epsilon / 7354433 FlyBaseID:FBgn0259714 Length:467 Species:Drosophila melanogaster
Sequence 2:XP_038936733.1 Gene:Ncam1 / 24586 RGDID:67378 Length:1136 Species:Rattus norvegicus


Alignment Length:571 Identity:120/571 - (21%)
Similarity:188/571 - (32%) Gaps:185/571 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    28 TDTGS---EGN---AGNVGGSTLNNVISEDP--EFTDVIENITVPAGRNVKLACSVKNLGSYKVA 84
            ||.|:   ||.   .|.:....:..:::..|  :....|.|.|...|::|.|.|.........::
  Rat   182 TDEGTYRCEGRILARGEINFKDIQVIVNVPPTVQARQSIVNATANLGQSVTLVCDADGFPEPTMS 246

  Fly    85 WMHFEQSAILTVHNHVITRNPRISVTHDKHDKHRTWF------LHINNVQEEDRGRYMCQINTVT 143
            |                |::.. .:.:::.|..:..|      |.|.||.:.|...|:|     .
  Rat   247 W----------------TKDGE-PIENEEEDDEKHIFSDDSSELTIRNVDKNDEAEYVC-----I 289

  Fly   144 AKTQYG------FVKVVVPPNIDDALTSSDIIVREGDNVTLRCKAKGSPEPTIKWKRDDGN---- 198
            |:.:.|      .:||...|.|  ....:...:...:.|||.|:|.|.|.|:|.|:....|    
  Rat   290 AENKAGEQDASIHLKVFAKPKI--TYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSE 352

  Fly   199 ------KIVINKTLEVH-----DLETDSLELERISRLHMGAYLCIASNGVPPSVSKRIKVSVDFS 252
                  :....:||:.|     .....||.|:.|.....|.|:|.|||.:... |:.:.:.|.::
  Rat   353 EKASWTRPEKQETLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQD-SQSMYLEVQYA 416

  Fly   253 PMV--------WIPHQLVGIPIGFNITLECFIEANPTSLNYWTRENDQMITESSKYKTETIPGHP 309
            |.:        |..:|:       |||.|.|  |.|::...|.|  |..:..||.|....|...|
  Rat   417 PKLQGPVAVYTWEGNQV-------NITCEVF--AYPSATISWFR--DGQLLPSSNYSNIKIYNTP 470

  Fly   310 SYKATMRLTITNVQSSDYGNYKCVAKNPRGDMDGNIKLYM----SSPPTTQPPPTTTTLR----R 366
            |   ...|.:|....:|:|||.|.|.|..|.......|..    |||...:..|.::|.:    .
  Rat   471 S---ASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPSSPSIDRVEPYSSTAQVQFDE 532

  Fly   367 TTTT--------------------------AAEIALDGYIN--------------TPLNGNGIGI 391
            ...|                          |.|..::|.:.              ..|||.|:|.
  Rat   533 PEATGGVPILKYKAEWKSLGEEAWHSKWYDAKEANMEGIVTIMGLKPETRYAVRLAALNGKGLGE 597

  Fly   392 VGEG------PTNSVIASGKSS---------------------------------IKYLSNLNEI 417
            :...      |.:|....|:.|                                 :||.:.|...
  Rat   598 ISAATEFKTQPVHSPPPQGEPSAPKLEGQMGEDGNSIKVNLIKQDDGGSPIRHYLVKYRAKLASE 662

  Fly   418 DKSKQKLTGSSP----KGFDWS------------KGKSSGSHGNLMASSWP 452
            .|.:.:|...|.    |..||:            :|||..:|.....|:.|
  Rat   663 WKPEIRLPSGSDHVMLKSLDWNAEYEVYVVAENQQGKSKAAHFVFRTSAQP 713

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-epsilonNP_001137799.1 IG_like 59..155 CDD:214653 21/107 (20%)
Ig 69..139 CDD:143165 14/75 (19%)
IG_like 165..249 CDD:214653 25/98 (26%)
IGc2 172..237 CDD:197706 24/79 (30%)
IG_like 267..348 CDD:214653 26/80 (33%)
Ig 270..339 CDD:299845 24/68 (35%)
Ncam1XP_038936733.1 IgI_1_NCAM-1 20..116 CDD:409451
Ig strand B 37..41 CDD:409451
Ig strand C 51..55 CDD:409451
Ig strand E 79..83 CDD:409451
Ig strand F 93..98 CDD:409451
Ig strand G 107..110 CDD:409451
IG_like 124..190 CDD:214653 3/7 (43%)
Ig strand B 135..139 CDD:409353
Ig strand C 148..152 CDD:409353
Ig strand E 172..176 CDD:409353
Ig strand F 186..191 CDD:409353 0/4 (0%)
IgI_3_NCAM-1 211..308 CDD:143207 23/118 (19%)
Ig strand B 231..235 CDD:143207 2/3 (67%)
Ig strand C 244..248 CDD:143207 1/19 (5%)
Ig strand E 271..275 CDD:143207 1/3 (33%)
Ig strand F 285..290 CDD:143207 2/9 (22%)
Ig strand G 298..301 CDD:143207 0/2 (0%)
IgI_NCAM-1 307..413 CDD:143277 27/108 (25%)
Ig strand B 326..330 CDD:143277 3/3 (100%)
Ig strand C 339..343 CDD:143277 1/3 (33%)
Ig strand E 379..383 CDD:143277 2/3 (67%)
Ig strand F 393..398 CDD:143277 2/4 (50%)
Ig strand G 406..409 CDD:143277 1/2 (50%)
Ig_3 422..494 CDD:404760 26/85 (31%)
Ig strand B 433..437 CDD:409353 2/10 (20%)
Ig strand C 446..450 CDD:409353 0/3 (0%)
Ig strand E 473..477 CDD:409353 1/3 (33%)
Ig strand F 487..492 CDD:409353 3/4 (75%)
FN3 509..606 CDD:238020 14/96 (15%)
fn3 619..701 CDD:394996 12/81 (15%)
Herpes_BLLF1 <842..1133 CDD:282904
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR12231
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.910

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