Protein Alignment DIP-epsilon and Lrit3

DIOPT Version :9

• Sequence 1: NP_001137799.1
• Gene: DIP-epsilon / 7354433
• FlyBaseID: FBgn0259714
• Length: 467
• Species: Drosophila melanogaster
• Sequence 2: NP_001274153.1
• Gene: Lrit3 / 242235
• MGIID: 2685267
• Length: 681
• Species: Mus musculus
• Alignment Length: 423
• Identity: 86/423 - (20%)
• Similarity: 134/423 - (31%)
• Gaps: 186/423 - (43%)

  Fly   163 LTSSDIIVREGDNVTLRCKAKGSPEPTIKWKRDDG---NKIVINKTLEVHDLETDSLELERISRL 224
            ::::.|....|.||.|||.|||.|.|.:.|.|.||   |..||.:: ....:....:.|..||..
Mouse   258 MSATKITSALGSNVLLRCDAKGHPTPQLTWTRSDGSTVNYTVIQES-PGEGIRWSIISLTSISHK 321

  Fly   225 HMGAYLCIASN--GVPPSVSKRIKVSVDFSPMVWIPHQLVGIPIGFNITLECFIEANPTSLNYWT 287
            ..|.|.|.|.|  |:..:|   :.|:|            ||   |...||      :|.|
Mouse   322 DAGDYRCKAKNLAGISEAV---VTVTV------------VG---GVTTTL------SPDS----- 357

  Fly   288 RENDQMITESSKYKTETIPGHPSYKATMRLTITNVQSSDYGNYKCVAKNPRGDMDG--------- 343
                          :|..||.|.                       .::|:..:.|
Mouse   358 --------------SERSPGEPP-----------------------EQHPQPGLGGSTPPSKSWL 385

  Fly   344 -------------NIKLYMS--SPPTTQPPP------TTTTLR-----RTTTTAAEIAL---DGY 379
                         :..||.|  |||.:..||      .||:::     ||..|:.:..|   .|.
Mouse   386 SPGLTSAPSYPTPSAALYTSTWSPPPSSLPPIFSAASATTSVQTSISGRTARTSHQPPLLHPGGK 450

  Fly   380 INTPLNGNG-------------IGIVGEGPT------------------------NSVIASGKSS 407
            .|..:..||             :.::.:...                        ||..::.:||
Mouse   451 SNAKIEKNGRKFPPLSASKKEELALLDQAAPMETNVTIKDLRVARETGVSVTLMWNSSSSTQESS 515

  Fly   408 I-----KY------LSNLNEIDKSKQKLTGSS----------PKG----------FDWSKGKSSG 441
            :     ||      |.|.::..|::..:.|..          |||          |..::.:..|
Mouse   516 VTVLYSKYGEKDLLLVNADDYGKNQATINGLEPGSQYVACVCPKGVGPREDLCITFSTNRVEGRG 580

  Fly   442 SHGNLM--ASSW------PLICCILALLTTHSC 466
            |..:|:  .:|.      ||||.:|..:....|
Mouse   581 SQWSLLLVVTSTACVIVVPLICFLLYKVCKLQC 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653
		Ig	69..139	CDD:143165
		IG_like	165..249	CDD:214653	30/88 (34%)
		IGc2	172..237	CDD:197706	26/69 (38%)
		IG_like	267..348	CDD:214653	11/102 (11%)
		Ig	270..339	CDD:299845	9/68 (13%)
Lrit3	NP_001274153.1	LRR 1. /evidence=ECO:0000255	56..79
		LRR_8	61..117	CDD:290566
		LRR 2. /evidence=ECO:0000255	80..103
		leucine-rich repeat	83..106	CDD:275378
		LRR 3. /evidence=ECO:0000255	104..128
		LRR_8	105..165	CDD:290566
		LRR_4	106..146	CDD:289563
		leucine-rich repeat	107..130	CDD:275378
		LRR_4	129..170	CDD:289563
		LRR 4. /evidence=ECO:0000255	129..151
		leucine-rich repeat	131..154	CDD:275378
		LRR 5. /evidence=ECO:0000255	152..175
		leucine-rich repeat	155..168	CDD:275378
		Ig	254..335	CDD:299845	27/77 (35%)
		IG_like	263..339	CDD:214653	28/76 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	350..391		10/88 (11%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	425..464		9/38 (24%)
		FN3	489..563	CDD:238020	13/73 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900