DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-epsilon and zig-3

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_509336.1	Gene:	zig-3 / 192088	WormBaseID:	WBGene00006980	Length:	251	Species:	Caenorhabditis elegans

Alignment Length:	217	Identity:	58/217 - (26%)
Similarity:	94/217 - (43%)	Gaps:	51/217 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   167 DIIVREGDNVTLRCKAKGSPEPTIKWKRDDGNKIVINKTLEVHD-------------LETDSLEL 218
            |..|..|::|||||....:|...|.|:: ||.:|..:|.|.|.:             :.|.|.::
Worm    52 DNTVSTGESVTLRCDVLSTPTGVIYWEK-DGQRIQGDKELNVFEKVLNAMGPTVESGIITSSYQI 115

  Fly   219 ERISRLHMGAYLCIASNGVPPSVSKRIKVSVD-----------FSPMVWIPHQLVGIPIGFNI-- 270
            ...:..|:|:|.|:|:|| ..:|....|:||:           .:|::     .:.....|.:
Worm   116 PCANLHHIGSYKCVATNG-HDTVESSAKISVEGQTVKCKSTRRSAPVI-----TMSTESRFELQD 174

  Fly   271 ---TLECFIEANPTSLNYWTRENDQMITESSKYKTETIPGHPSYKATMRLTITNVQSSDYGNYKC 332
               ||.|  .|:..:...|..|:.::..:|.:|  |.:|...       |.|..:|.||.|:|.|
Worm   175 NAATLIC--RADRRANWNWMFEDKKIDFDSGRY--ELLPSGD-------LLIRKIQWSDMGSYFC 228

  Fly   333 VAKNPRGDMDGNIKLYMSSPPT 354
            :|.|..|:..|...||    ||
Worm   229 IAHNKYGESRGETFLY----PT 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653
		Ig	69..139	CDD:143165
		IG_like	165..249	CDD:214653	28/94 (30%)
		IGc2	172..237	CDD:197706	23/77 (30%)
		IG_like	267..348	CDD:214653	23/85 (27%)
		Ig	270..339	CDD:299845	20/73 (27%)
zig-3	NP_509336.1	I-set	45..145	CDD:254352	28/94 (30%)
		Ig	61..142	CDD:143165	24/82 (29%)
		IG_like	177..244	CDD:214653	22/77 (29%)
		Ig	<191..237	CDD:299845	17/54 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810