DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-epsilon and zig-2

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_510069.1	Gene:	zig-2 / 192087	WormBaseID:	WBGene00006979	Length:	238	Species:	Caenorhabditis elegans

Alignment Length:	226	Identity:	56/226 - (24%)
Similarity:	90/226 - (39%)	Gaps:	63/226 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   164 TSSDIIVREGDNVTLRCKAKGSPEPTIKWKRDDGNKIVINKTLEVHD-LETDSLELERISRL--- 224
            |.:|..|..|:...|.|.|.|:|.|:|.|:. :|.:|...:|..|:: :..|..::...:.:
Worm    38 TPNDSNVTFGEKFVLSCGANGAPLPSIYWEL-NGMRIQGEETSNVYENILNDGKQVSNAAMVSSH 101

  Fly   225 ---------HMGAYLCIASNGVP--PSVSK------------------RIKVSVDFSPMVWIPHQ 260
                     :.|||.||..||:.  ..|:|                  .|.::|||.
Worm   102 YRIPCATARNSGAYKCIIDNGLTKLEHVAKVFVGGNKTNCALNDNGAPFISMTVDFR-------- 158

  Fly   261 LVGIPIGFN-ITLECFIEANPTSLNYWTRENDQMIT-ESSKYKTETIPGHPSYKATMRLTITNVQ 323
               :.|..| :.|.|..|   |:..:...:.:|::| :..:|:.     .||..    |.|.|:.
Worm   159 ---LEISNNAVALSCRSE---TATEWSWHKGEQLLTNDGERYQM-----FPSGD----LIIRNIS 208

  Fly   324 SSDYGNYKCVAKNPRGDMDGNIKLYMSSPPT 354
            .||.|.|.|.|:|..|:......||    ||
Worm   209 WSDMGEYNCTARNHFGETTAITFLY----PT 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653
		Ig	69..139	CDD:143165
		IG_like	165..249	CDD:214653	26/116 (22%)
		IGc2	172..237	CDD:197706	20/77 (26%)
		IG_like	267..348	CDD:214653	21/82 (26%)
		Ig	270..339	CDD:299845	19/69 (28%)
zig-2	NP_510069.1	I-set	34..134	CDD:254352	26/96 (27%)
		Ig	34..121	CDD:299845	22/83 (27%)
		Ig	<179..232	CDD:299845	16/61 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810