DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-epsilon and pxn-1

DIOPT Version :9

Sequence 1:NP_001137799.1 Gene:DIP-epsilon / 7354433 FlyBaseID:FBgn0259714 Length:467 Species:Drosophila melanogaster
Sequence 2:NP_505188.3 Gene:pxn-1 / 191484 WormBaseID:WBGene00004256 Length:1285 Species:Caenorhabditis elegans


Alignment Length:395 Identity:94/395 - (23%)
Similarity:144/395 - (36%) Gaps:130/395 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    66 GRNVKLACSVKNLGSYKVAWMH----FEQSAI--LTVHNHVITRNPR------ISVTHD-KHDKH 117
            |..:||.|: ||..|..|.||:    .:.|::  ..:|:.||| .||      ::.|:| .|..|
 Worm   238 GEEIKLTCA-KNSSSKLVVWMYENVEVDSSSLDGYEIHDTVIT-VPRKTNVNFMTCTYDFDHIPH 300

  Fly   118 RTWFLHINNVQEEDRGRYMCQINTVTAKTQYGFVKVVVPPNIDDALTSSDIIVREGDNVTLRCKA 182
                 |....|.:.:|.              |..:....|.        |...|||..|.:.|:.
 Worm   301 -----HRRLRQSQHQGN--------------GSPQFTYKPR--------DNSFREGSEVKVNCEV 338

  Fly   183 KGSPEPTIKW-----------KRDDGNKIVINKTLEVHD-LETDSLELERISRLHMGAYLCIASN 235
            .|:|:|||.|           ||..|   :.|..|.::. ||.||           |.|.|.|.|
 Worm   339 MGNPKPTINWYHNGKRFISSRKRQLG---LSNNVLRIYPFLEEDS-----------GRYTCEAVN 389

  Fly   236 GVPPSVSK-RIKVSVDF----SPMVWIPHQLVGIPIGFNITLECFIEANPTSLNYWTRENDQMIT 295
                ||.| |...|:|.    .|.::...|.|...:|.::...|....||.....|:        
 Worm   390 ----SVGKVRHAFSLDLISSVPPNIYEGPQSVSQNLGGSVVFVCKANGNPVPDYTWS-------- 442

  Fly   296 ESSKYKTETIPGHPSYKATM-----RLTITNVQSSDYGNYKCVAKNPRGDMDGNIKLYMSSPPTT 355
                :...|| ||...:..:     .|.|:|::..|.|.|.|:|.||.|.|..:.||        
 Worm   443 ----FDGSTI-GHIKGRFMVSDDGTELRISNIEKKDEGYYSCMAGNPVGAMSADAKL-------- 494

  Fly   356 QPPPTTTTLRRTTTTAAEIALDGYINTPLNGNGIGIVGEGPTNSVIASGKSSIKYLSNLNEIDKS 420
                  |.:...|..||...:|                |....::....:.:::     |.::|:
 Worm   495 ------TVIGGETRKAAAPQID----------------EELLRAIAQKARQNVE-----NAVEKT 532

  Fly   421 KQKLT 425
            :::||
 Worm   533 RKQLT 537

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-epsilonNP_001137799.1 IG_like 59..155 CDD:214653 25/101 (25%)
Ig 69..139 CDD:143165 23/82 (28%)
IG_like 165..249 CDD:214653 30/96 (31%)
IGc2 172..237 CDD:197706 24/76 (32%)
IG_like 267..348 CDD:214653 22/85 (26%)
Ig 270..339 CDD:299845 18/73 (25%)
pxn-1NP_505188.3 LRRNT 23..51 CDD:279764
leucine-rich repeat 35..53 CDD:275380
LRR_8 52..112 CDD:290566
LRR_4 53..93 CDD:289563
leucine-rich repeat 54..77 CDD:275380
LRR_4 77..120 CDD:289563
leucine-rich repeat 78..101 CDD:275380
leucine-rich repeat 102..117 CDD:275380
LRR_8 123..182 CDD:290566
leucine-rich repeat 125..148 CDD:275380
leucine-rich repeat 149..172 CDD:275380
I-set 315..400 CDD:254352 31/110 (28%)
IGc2 328..392 CDD:197706 25/81 (31%)
IG_like 414..496 CDD:214653 25/108 (23%)
Ig 420..496 CDD:299845 23/102 (23%)
An_peroxidase 634..1181 CDD:281139
peroxidasin_like 757..1203 CDD:188658
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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