DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-epsilon and Cntn3

DIOPT Version :9

Sequence 1:NP_001137799.1 Gene:DIP-epsilon / 7354433 FlyBaseID:FBgn0259714 Length:467 Species:Drosophila melanogaster
Sequence 2:NP_032805.2 Gene:Cntn3 / 18488 MGIID:99534 Length:1028 Species:Mus musculus


Alignment Length:510 Identity:118/510 - (23%)
Similarity:199/510 - (39%) Gaps:123/510 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    18 CLIASSVALSTDTGSEGNAGNVGGSTLNNVISED---PEFTDVIE---NITVPA--GRNVKLACS 74
            |::.|:|   |:|       .|.||....|:..|   .|:...||   ..|:||  |..|:|.|.
Mouse   196 CVVTSTV---TNT-------RVLGSPTPLVLRSDGVMGEYEPKIEVQFPETLPAAKGSTVRLECF 250

  Fly    75 VKNLGSYKVAWMHFEQSAILTVHNHVITRNPRISVTHDKHDKHRTWFLHINNVQEEDRGRYMCQI 139
            .  ||: .|..:::.:|..:...|.:..|.             ....|.|.|.|:||.|.|.|..
Mouse   251 A--LGN-PVPQINWRRSDGMPFPNKIKLRK-------------FNGMLEIQNFQQEDTGSYECIA 299

  Fly   140 NTVTAK-TQYGFVKVVVPPNIDDALTSSDIIVREGDNVTLRCKAKGSPEPTIKWKRDDGNKIVIN 203
            .....| ...|.:.....|.....|...:|.|.  |::...|:|.|.|:|:.:|.: :|:.:|:.
Mouse   300 ENSRGKNVARGRLTYYAKPYWLQLLRDVEIAVE--DSLYWECRASGKPKPSYRWLK-NGDALVLE 361

  Fly   204 KTLEVHDLETDSLELERISRLHMGAYLCIASN--GVPPSVSKRIKV---SVDFS--PMVWIPHQL 261
            :.:::   |..:|.:..::....|.:.|||.|  |:..| |..:||   :.|||  ||    .::
Mouse   362 ERIQI---ENGALTITNLNVTDSGMFQCIAENKHGLIYS-SAELKVVASAPDFSRNPM----KKM 418

  Fly   262 VGIPIGFNITLECFIEANPTSLNYWTRENDQMITESSKYKTETIPGHPSYKATMRLTITNVQSSD 326
            |.:.:|..:.|:|...|:|.:|::| ::.|.|:.|.::.         |:.....|.|.||..:|
Mouse   419 VQVQVGSLVILDCKPRASPRALSFW-KKGDMMVREQARV---------SFLNDGGLKIMNVTKAD 473

  Fly   327 YGNYKCVAKNPRGDMDGNIKLYMSSPPTTQPPPTTTTLRRTTTTAA-----------------EI 374
            .|.|.|.|:|..|..:|...|.::.       ||...|..:....|                 :|
Mouse   474 AGTYTCTAENQFGKANGTTHLVVTE-------PTRIILAPSNMDVAVGESVILPCQVQHDPLLDI 531

  Fly   375 ALDGYINTPL-----NGNGIGIVGEGPTNSVIASG---KSSIKYL----SNLNEIDKSKQKLTGS 427
            ....|.|..|     :|:....||...:..::...   |.|.||:    :.::.:..:.:.:...
Mouse   532 MFAWYFNGALTDFKKDGSHFEKVGGSSSGDLMIRNIQLKHSGKYVCMVQTGVDSVSSAAELIVRG 596

  Fly   428 SP---------------KGFDWSKGKSSGSHGNLMASSWPLICCILALLTTHSCG 467
            ||               ....|::|..|.|         |:|...:...|..|.|
Mouse   597 SPGPPENVKVDEITDTTAQLSWTEGTDSHS---------PVISYAVQARTPFSVG 642

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-epsilonNP_001137799.1 IG_like 59..155 CDD:214653 25/101 (25%)
Ig 69..139 CDD:143165 18/69 (26%)
IG_like 165..249 CDD:214653 23/88 (26%)
IGc2 172..237 CDD:197706 16/66 (24%)
IG_like 267..348 CDD:214653 23/80 (29%)
Ig 270..339 CDD:299845 20/68 (29%)
Cntn3NP_032805.2 Ig 25..120 CDD:416386
Ig strand A 27..31 CDD:409353
Ig strand A' 34..39 CDD:409353
Ig strand B 45..53 CDD:409353
Ig strand C 58..64 CDD:409353
Ig strand C' 66..69 CDD:409353
Ig strand D 76..80 CDD:409353
Ig strand E 82..88 CDD:409353
Ig strand F 95..104 CDD:409353
Ig strand G 107..120 CDD:409353
Ig 129..214 CDD:416386 8/27 (30%)
Ig strand A 130..135 CDD:409353
Ig strand B 139..145 CDD:409353
Ig strand C 153..159 CDD:409353
Ig strand C' 164..166 CDD:409353
Ig strand D 171..176 CDD:409353
Ig strand E 179..183 CDD:409353
Ig strand F 193..201 CDD:409353 1/4 (25%)
Ig strand G 203..214 CDD:409353 5/17 (29%)
Ig 227..315 CDD:416386 26/103 (25%)
Ig strand A 227..232 CDD:409353 2/4 (50%)
Ig strand A' 235..240 CDD:409353 2/4 (50%)
Ig strand B 243..252 CDD:409353 3/10 (30%)
Ig strand C 258..262 CDD:409353 0/3 (0%)
Ig strand C' 265..267 CDD:409353 0/1 (0%)
Ig strand D 276..279 CDD:409353 1/15 (7%)
Ig strand E 280..285 CDD:409353 1/4 (25%)
Ig strand F 293..301 CDD:409353 3/7 (43%)
Ig strand G 304..315 CDD:409353 2/10 (20%)
Ig 320..403 CDD:416386 22/89 (25%)
Ig strand A' 326..330 CDD:409353 0/3 (0%)
Ig strand B 334..342 CDD:409353 1/7 (14%)
Ig strand C 348..353 CDD:409353 1/4 (25%)
Ig strand C' 355..358 CDD:409353 1/2 (50%)
Ig strand D 363..367 CDD:409353 0/6 (0%)
Ig strand E 369..374 CDD:409353 1/4 (25%)
Ig strand F 383..390 CDD:409353 3/6 (50%)
Ig strand G 394..403 CDD:409353 2/9 (22%)
Ig 408..496 CDD:416386 30/101 (30%)
Ig strand A 408..413 CDD:409353 3/4 (75%)
Ig strand A' 416..421 CDD:409353 1/4 (25%)
Ig strand B 425..432 CDD:409353 1/6 (17%)
Ig strand C 440..444 CDD:409353 2/4 (50%)
Ig strand D 458..461 CDD:409353 0/2 (0%)
Ig strand E 462..467 CDD:409353 1/4 (25%)
Ig strand F 475..483 CDD:409353 4/7 (57%)
Ig strand G 489..496 CDD:409353 2/6 (33%)
Ig 498..598 CDD:416386 15/106 (14%)
Ig strand A 498..504 CDD:409353 2/12 (17%)
Ig strand A' 507..512 CDD:409353 0/4 (0%)
Ig strand B 515..523 CDD:409353 0/7 (0%)
Ig strand C 532..536 CDD:409353 0/3 (0%)
Ig strand E 560..564 CDD:409353 0/3 (0%)
Ig strand F 573..580 CDD:409353 2/6 (33%)
Ig strand G 587..591 CDD:409353 0/3 (0%)
FN3 598..695 CDD:238020 10/54 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 684..714
FN3 703..795 CDD:238020
FN3 805..898 CDD:238020
FN3 906..991 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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