DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-epsilon and zig-4

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_509335.1	Gene:	zig-4 / 181051	WormBaseID:	WBGene00006981	Length:	253	Species:	Caenorhabditis elegans

Alignment Length:	301	Identity:	63/301 - (20%)
Similarity:	110/301 - (36%)	Gaps:	101/301 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 MHFE-QSAILTVHNHVITRNPRISVTHDKHDKHRTWFLHINNVQEEDRGRYMCQINTVTAKTQYG 149
            ||.| .||::|:.|.:.|                                     |.:|:..:
Worm    20 MHAEMHSAVVTLANEIDT-------------------------------------NYLTSPAK-- 45

  Fly   150 FVKVVVPPNIDDALTSSDIIVREGDNVTLRCKAKGSPEPTIKWKRDDGNKIVINKTLEVHD---- 210
             :|:|.|  ::.||      :..|:...|||....:|..||.|| .:|..|..:..|.|.:
Worm    46 -IKIVAP--LESAL------IPGGETYQLRCDIMSTPAATIHWK-FNGKLIQGSNELNVEEKLLN 100

  Fly   211 ---------LETDSLELERISRLHMGAYLCIASNGVPPSVSKRIKVSVD-----------FSPMV 255
                     :....|.::..|..:.|.|.|:..|| ..::....:|.::           .:|.:
Worm   101 FGKAIVDTGIVASILTIQCPSAENSGTYSCVGYNG-HQTIETVAEVEIEGEASGCRSNHKSAPEI 164

  Fly   256 --WIP--HQLVGIPIGFNI-TLECFIEANPTSLNYWTRENDQMITESSKYKTETIPGHPSYKATM 315
              |..  .::.|     |: ||.|  .|| ..:::....||:::..:.|:   |:..:..
Worm   165 VFWTDSRFEMTG-----NVATLVC--RAN-QQVDWVWMSNDELVKNNDKF---TVLSNGD----- 213

  Fly   316 RLTITNVQSSDYGNYKCVAKNPRGDMDGNIKLYMSSPPTTQ 356
             |.|.|:...|.|.|.|:|:|..|:......||    ||.:
Worm   214 -LVIKNIVWDDMGTYTCIARNQFGEARQETFLY----PTAK 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	11/69 (16%)
		Ig	69..139	CDD:143165	8/53 (15%)
		IG_like	165..249	CDD:214653	21/96 (22%)
		IGc2	172..237	CDD:197706	19/77 (25%)
		IG_like	267..348	CDD:214653	20/81 (25%)
		Ig	270..339	CDD:299845	18/69 (26%)
zig-4	NP_509335.1	I-set	47..147	CDD:254352	26/109 (24%)
		Ig	65..144	CDD:143165	19/80 (24%)
		IG_like	176..245	CDD:214653	21/85 (25%)
		Ig	<193..238	CDD:299845	14/53 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810