DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DIP-epsilon and rig-3

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_509155.1	Gene:	rig-3 / 180958	WormBaseID:	WBGene00004370	Length:	487	Species:	Caenorhabditis elegans

Alignment Length:	386	Identity:	88/386 - (22%)
Similarity:	139/386 - (36%)	Gaps:	89/386 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 CLIASSVALSTDTGSEGNAGNVGGSTLNNVISEDPEFTDVIENITVPAGRNVKLAC---SVKNLG 79
            ||..|:|:.| |:.|...|..:       |||.:....|. ..|||..|:.:.::|   |.:.:.
Worm    15 CLFVSAVSAS-DSPSSNEANPI-------VISSEAMDYDT-NTITVREGKKLMVSCVFESDEQIH 70

  Fly    80 SYKVAWMHFEQSAILTVHNHVITRNPRI--SVTHDKHDKHRTWFLHINNVQEEDRGRYMCQINTV 142
            ...:.|..      ...:|.....||.:  .:.::|..|||...||.::|...|.|.|.|...|.
Worm    71 KSDLLWKQ------ANGNNIDGESNPSLFSVILNEKGSKHRKTSLHFSSVHTRDTGLYTCTGRTA 129

  Fly   143 TAKTQYGFVKVVVPPNID--DALTSSDIIVREGDNVTLRCKAKG--SPEPTIKWKRDD------- 196
            ..:.....:|:||.|.|:  |..|....::  |:.:|:.|..||  ..||.|:....:
Worm   130 GGENFEKTIKLVVLPAIEWNDKDTVKGALL--GEPITIDCGVKGPSGKEPMIQMTNGNGEPLDEE 192

  Fly   197 -----GNKIVINK-------------TLEVHDLETDSLELERISRLHMGAYLCIASNGVPPSVSK 243
                 ||:..|:.             |:|:|. ||...|...:.|                   |
Worm   193 IWTIAGNEATIDSLKKEHAELTVSCITIEMHQ-ETSKEEFPVVDR-------------------K 237

  Fly   244 RIKVSV----DFSPMVWIPHQLVGIPIGFNITLECFIEAN-----PTSLNYWTRENDQMITESSK 299
            .:.:.|    :|.....:.:.::.     |...:..|..|     |...:|.....|:.|..|.|
Worm   238 DVNIEVYTLPEFETEESVQYTVID-----NHVRDAIIYCNVTHSFPPVRHYTFYHGDEEIKMSDK 297

  Fly   300 YKTETIPGHPSYKATMRLTITNVQSSDYGNYKCVAKNPRGDMDGNIKLYMSSPPTTQPPPT 360
            :......|   ......|.|.||..:|.|.|||.|.|.:......|.|..::.| .:|..|
Worm   298 FNIFVNVG---VSQGAHLKIHNVNENDLGTYKCEANNIKAKSYHTIHLREANAP-AEPKVT 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	23/100 (23%)
		Ig	69..139	CDD:143165	17/74 (23%)
		IG_like	165..249	CDD:214653	19/110 (17%)
		IGc2	172..237	CDD:197706	18/91 (20%)
		IG_like	267..348	CDD:214653	22/85 (26%)
		Ig	270..339	CDD:299845	20/73 (27%)
rig-3	NP_509155.1	IG_like	48..142	CDD:214653	23/99 (23%)
rig-3	NP_509155.1	Ig	267..341	CDD:319273	20/76 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810