DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DIP-epsilon and zig-8

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_499714.1	Gene:	zig-8 / 176732	WormBaseID:	WBGene00006985	Length:	268	Species:	Caenorhabditis elegans

Alignment Length:	279	Identity:	67/279 - (24%)
Similarity:	108/279 - (38%)	Gaps:	55/279 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 CLIASSVALSTDTGS----------EGNAGNVGGSTLNNVISEDPEFTDVIENITVPAGRNVKLA 72
            |:|..|...:|..|:          |.:.......|:.||::|:|.:                |.
Worm     8 CVILFSFLYATGHGASEEVMACLRQERSRVENPSQTIVNVVAENPAY----------------LH 56

  Fly    73 CSVKNLGSYKVAWMHFEQSAILTVHNHVITRNPRISVTHDKHDKHRTWFLHINNVQEEDRGRYMC 137
            |||.....:::||......|:||..|...||:||..|:....:   .|.|::...:::|.|.|:|
Worm    57 CSVPPDAEHEIAWTRVSDGALLTAGNRTFTRDPRWQVSKKSAN---IWVLNLRRAEQQDSGCYLC 118

  Fly   138 QINTVTAKTQYGFVKVVVPPNIDDALTSSDIIVRE---------GDNVTLRCKAKGSPEP----T 189
            :||.........::||:.||     |.|...:.::         ||.|.|.|....:.:.    .
Worm   119 EINDKHNTVYAVYLKVLEPP-----LPSPSSLQKKSTKLMANMSGDEVVLNCTVTSTDKDEEVLD 178

  Fly   190 IKWKRDDGNKIVINKTLE-VHDLETDS---LELERISRLHM---GAYLCIASNGVPPSVSKRIKV 247
            :.|.| |||.|..|.|.: :..::.|:   :|..||.:..|   |.|.|..|......:....|.
Worm   179 VVWTR-DGNTINFNDTEKYILKVKRDAGVVIETMRIRKATMEDDGNYACEHSQQKASQIVHINKA 242

  Fly   248 SVDFSPMVWIPHQLVGIPI 266
            ....|.....|..:..|.|
Worm   243 EAQTSNSATFPCSIFSISI 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	25/95 (26%)
		Ig	69..139	CDD:143165	21/69 (30%)
		IG_like	165..249	CDD:214653	24/103 (23%)
		IGc2	172..237	CDD:197706	22/84 (26%)
		IG_like	267..348	CDD:214653	67/279 (24%)
		Ig	270..339	CDD:299845
zig-8	NP_499714.1	IG_like	55..134	CDD:214653	23/81 (28%)
		Ig	55..129	CDD:143165	23/76 (30%)
		ig	158..229	CDD:278476	21/71 (30%)
		IG_like	158..227	CDD:214653	20/69 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810