DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-epsilon and rig-5

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_001251131.1	Gene:	rig-5 / 172791	WormBaseID:	WBGene00004372	Length:	482	Species:	Caenorhabditis elegans

Alignment Length:	335	Identity:	111/335 - (33%)
Similarity:	158/335 - (47%)	Gaps:	42/335 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 GRNVKLACSVKNLGSYKVAWMHFEQ-SAILTVHNHVITR------NPRISVTHDKHDKHRTWFLH 123
            |::|...|.|.:|||:.||::..:. ..:|:....|..|      .|||.      |.|..|.|.
Worm    99 GQDVDFTCIVNDLGSHMVAFVKADSPPRLLSFDEKVFRRRNKYELKPRIG------DLHNEWVLT 157

  Fly   124 INNVQEEDRGRYMCQINTVTAKTQYGFVKVVVPPNIDDALTSSDIIVREGDNVTLRCKAKGSPEP 188
            |.||||.|||.|.|||||.......|.:.|.|||.:..: |.:.:.||||:||:|.|||.|:|.|
Worm   158 IKNVQESDRGNYSCQINTEPITLSTGELDVKVPPVVSRS-TPAAVEVREGNNVSLTCKADGNPTP 221

  Fly   189 TIKWKRDDGNKIVINKT--LEVHDLETDSLELERISRLHMGAYLCIASNGVPPSVSKRIKVSVDF 251
            |:.|:|.|...|..|..  ..........|.|.::||.||..|||:||||:||..|..:|:.|.|
Worm   222 TVIWRRQDRQIIRYNGATGFGASVFHGPVLHLTKVSRKHMSEYLCVASNGIPPDESWTVKLLVTF 286

  Fly   252 SPMVWIPHQLVGIPIGFNITLECFIEANPTSLNYWTRENDQMITESSKYKTETIPGHPSYKATMR 316
            .|:|....:.|...:|....:.|..||.|.....|.::.:.:...::...|.|:.|  .|.:...
Worm   287 PPLVQAQSETVQASVGSMARMVCTTEAWPRPEMGWEKDGEPVYESNNVAMTHTVSG--QYHSVHI 349

  Fly   317 LTITNVQSSDYGNYKCVAKNPRGDMDGNIKLYMSSPPTTQPPPTTTTLRRTTTTAAEIALDGYIN 381
            |.|.|||||.:|.|:|||||..|                        :..:..|..:|:.:.:.|
Worm   350 LEIRNVQSSHFGVYRCVAKNDNG------------------------IHHSQVTLNQISHNHFTN 390

  Fly   382 TPLNGNGIGI 391
            :.|...|.|:
Worm   391 SNLIPEGSGM 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	35/95 (37%)
		Ig	69..139	CDD:143165	28/76 (37%)
		IG_like	165..249	CDD:214653	36/85 (42%)
		IGc2	172..237	CDD:197706	29/66 (44%)
		IG_like	267..348	CDD:214653	25/80 (31%)
		Ig	270..339	CDD:299845	23/68 (34%)
rig-5	NP_001251131.1	IG_like	92..189	CDD:214653	35/95 (37%)
		Ig_3	191..270	CDD:372822	31/79 (39%)
		IG	294..380	CDD:214652	26/111 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	77	1.000	Domainoid score	I5731
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	196	1.000	Inparanoid score	I2513
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	1	1.000	-	-		otm14489
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12231
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3058
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	11.100