DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-epsilon and zig-7

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_491451.2	Gene:	zig-7 / 172096	WormBaseID:	WBGene00006984	Length:	239	Species:	Caenorhabditis elegans

Alignment Length:	246	Identity:	54/246 - (21%)
Similarity:	93/246 - (37%)	Gaps:	72/246 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 NNVISEDPEFTDVIENITVPAGRNVK-LACSVKNLGSY-KVAWMHFEQSAILTVHNHVITRNPRI 107
            |..:...||......|.|:.|  |:: |.|..:|||.: .|.:..|.:.:...|....:.:.
Worm    28 NLAVVGSPESHVGTPNKTLYA--NIQNLWCGAQNLGEHIDVEYGEFTRLSDGKVFKGTVNQG--- 87

  Fly   108 SVTHDKHDKHRTWFLHINNVQEEDRGRYMCQINTVTAKTQYGFVKVVVPPNID--DALTSSDIIV 170
                       ..:|.|.....:..|||.|::.|:..:...|.:.:.:||.:|  .|:..|:::.
Worm    88 -----------KVYLEIGKASVKVAGRYRCEVRTLDKEIHSGNLIIYMPPVLDFPAAVRVSEVLN 141

  Fly   171 R-------------EGDNVTLRCKAKGSPEPTIKWKRD------------DGNKIVINKTLEVHD 210
            .             .|:.:.|.|....:|||.::|:::            |||.:::|...|.
Worm   142 ARPPHVIGAERRGLHGERMVLECPVLANPEPMVRWEKNGEPLGNSDSIEYDGNNLILNSLTED-- 204

  Fly   211 LETDSLELERISRLHMGAYLCIASNGVPPSVSKRIKVSVDFSPMVWIPHQL 261
                          |:|.|.||..|..|        :.|| .|.  ||||:
Worm   205 --------------HIGKYRCIGDNSFP--------LFVD-GPA--IPHQI 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	20/97 (21%)
		Ig	69..139	CDD:143165	14/71 (20%)
		IG_like	165..249	CDD:214653	20/108 (19%)
		IGc2	172..237	CDD:197706	18/76 (24%)
		IG_like	267..348	CDD:214653
		Ig	270..339	CDD:299845
zig-7	NP_491451.2	IGc2	157..216	CDD:197706	17/74 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910