DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-epsilon and AgaP_AGAP009253

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_320040.3	Gene:	AgaP_AGAP009253 / 1280215	VectorBaseID:	AGAP009253	Length:	258	Species:	Anopheles gambiae

Alignment Length:	212	Identity:	61/212 - (28%)
Similarity:	89/212 - (41%)	Gaps:	18/212 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 ISEDPEF-TDVIENITVPAGRNVKLACSVKNLGSYKVAWMHFEQSAILTVHNHVITRNPRISVTH 111
            :...|.| ....:|||...|:...|.|.|||:|:..|:|:......:|||.....|.:.|....|
Mosquito    48 LDRGPHFDLSASKNITALVGKTAYLNCRVKNIGNKTVSWVRHRDIHLLTVGRFTYTSDQRFQAVH 112

  Fly   112 DKHDKHRTWFLHINNVQEEDRGRYMCQINTVTAKTQYGFVKVVVPPNIDDALTSSDIIVREGDNV 176
            :....  .|.|.|...|:.|.|.|.|||:|........|:.||.|  |...:...|:.:..|..|
Mosquito   113 NPQTD--DWSLQIRYPQKRDTGVYECQISTTPPVGHSMFLAVVEP--ITTIVGVPDLYINTGSTV 173

  Fly   177 TLRCKAKGSPEP--TIKWKRD-----------DGNKIVINKTLEVHDLETDSLELERISRLHMGA 228
            .|.|..:.||||  ||.|..:           |..:..::...|..:|.|..|.::|......|.
Mosquito   174 NLTCIVRNSPEPPSTIFWTHNNQVSGEGEINYDSPRGGVSVITEKGELTTSYLLIQRARTTDSGK 238

  Fly   229 YLCIASNGVPPSVSKRI 245
            |:|..||..|.:::..|
Mosquito   239 YVCSPSNADPSTINVHI 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	31/95 (33%)
		Ig	69..139	CDD:143165	22/69 (32%)
		IG_like	165..249	CDD:214653	25/94 (27%)
		IGc2	172..237	CDD:197706	22/77 (29%)
		IG_like	267..348	CDD:214653
		Ig	270..339	CDD:299845
AgaP_AGAP009253	XP_320040.3	IG_like	59..147	CDD:214653	29/89 (33%)
		Ig	62..143	CDD:299845	28/82 (34%)
		IG_like	163..255	CDD:214653	24/91 (26%)
		IGc2	170..246	CDD:197706	21/75 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810