DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DIP-epsilon and AgaP_AGAP009248

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_320025.4	Gene:	AgaP_AGAP009248 / 1280202	VectorBaseID:	AGAP009248	Length:	243	Species:	Anopheles gambiae

Alignment Length:	233	Identity:	67/233 - (28%)
Similarity:	94/233 - (40%)	Gaps:	33/233 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 VGG--STLNNVISED------------PEF-TDVIENITVPAGRNVKLACSVKNLGSYKVAWMHF 88
            :||  |..|.:...|            |.| ....:|||...|:...|.|.|||:|:..|:|:..
Mosquito    15 LGGNCSAFNEIYDSDESNLLRTPLDRGPHFDLSASKNITALVGKTAYLNCRVKNIGNKTVSWVRH 79

  Fly    89 EQSAILTVHNHVITRNPRISVTHDKHDKHRTWFLHINNVQEEDRGRYMCQINTVTAKTQYGFVKV 153
            ....:|||.....|.:.|....|:....  .|.|.|...|:.|.|.|.|||:|........|:.|
Mosquito    80 RDIHLLTVGRFTYTSDQRFQAVHNPQTD--DWSLQIRYPQKRDTGVYECQISTTPPVGHSMFLAV 142

  Fly   154 VVPPNIDDALTSSDIIVREGDNVTLRCKAKGSPEP--TIKWKRDD---------GNKIVINKTLE 207
            |.|  |...:...|:.:.....|.|.|..:.||||  ||.|..::         |...||.|..|
Mosquito   143 VEP--ITTIVGVPDLYINTDSTVNLTCIVRNSPEPPSTIFWTHNNQEINYDSPRGGVSVITKKGE 205

  Fly   208 VHDLETDSLELERISRLHMGAYLCIASNGVPPSVSKRI 245
               :.|..|.::|......|.|:|..||..|.:::..|
Mosquito   206 ---MTTSYLLIQRARTTDSGKYVCSPSNADPSTINVHI 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	31/95 (33%)
		Ig	69..139	CDD:143165	22/69 (32%)
		IG_like	165..249	CDD:214653	26/92 (28%)
		IGc2	172..237	CDD:197706	23/75 (31%)
		IG_like	267..348	CDD:214653
		Ig	270..339	CDD:299845
AgaP_AGAP009248	XP_320025.4	IG_like	49..137	CDD:214653	29/89 (33%)
		Ig	52..133	CDD:299845	28/82 (34%)
		IG_like	153..240	CDD:214653	25/89 (28%)
		IGc2	160..231	CDD:197706	22/73 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810