DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-epsilon and AgaP_AGAP009596

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_318623.4	Gene:	AgaP_AGAP009596 / 1278969	VectorBaseID:	AGAP009596	Length:	658	Species:	Anopheles gambiae

Alignment Length:	404	Identity:	92/404 - (22%)
Similarity:	151/404 - (37%)	Gaps:	98/404 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 LNNVISED---PEFTDVIEN-ITVP----AGRNVKLACSVKNLGSYKVAWMHFEQSAILTVHNHV 100
            :|.||.:|   ....||||| :..|    :..|....|...|....:..    |.|.:|.:|...
Mosquito   168 INGVIVDDQYEQNSGDVIENRLLWPTIQRSDLNAIFTCQTMNTKLVEPK----ETSYVLDMHLKP 228

  Fly   101 IT---RNPRISVTHDKH------------DKHRTWF----------------------LHINNVQ 128
            :|   .||..::..||.            :...||:                      |......
Mosquito   229 LTIKVINPPATLVADKRYEIVCQSTGSRPNAIITWYKGKRQMRRTRDETVDHNTTTSTLSFAPTT 293

  Fly   129 EEDRGRYMCQ-----INTVTAKTQYGFVKVVVPPNIDDALTSSDII--VREGDNVTLRCKAKGSP 186
            |:|.....|:     :|.:..:|.:. :.||.||.:...|..:.::  ::|||:|...|..:.:|
Mosquito   294 EDDGKTLTCRAENPNVNGLFLETDWK-MNVVYPPMVTIQLGPTLVVDDIKEGDDVYFECHVRANP 357

  Fly   187 EPTIKWKRDD--GNKIVINKTLEVHDLET-DSLELERISRLHMGAYLCIASNGVPPSVSKRIKVS 248
            :    |||..  .|.:::........::: .||.|:::::...|.|.|.|.|....:||.:..:.
Mosquito   358 D----WKRLQWFHNDVLLQYNGSARIIQSGQSLVLQKVTKQSAGYYACSAINAEGETVSDQQHLR 418

  Fly   249 VDFSPMVWIPHQLVGIPIGFNITLECFIEANPTSLNYWTRENDQMITESSKYKTETIP--GHPSY 311
            |..:....|   |:|.....|:.:.|.|.|:|.:.::..|.|:         ..|.:|  .| .|
Mosquito   419 VKRNNRNAI---LIGASRNENVEIPCHIFADPPARSFHWRFNN---------SAEILPVDAH-RY 470

  Fly   312 KATMRLTITN---VQSSDYGNYKCVAKNPRGDMDGNIKLYMSSPPTTQ------PPPTTT-TLRR 366
            .:...::|.|   |...|:|...|.|.|..|.        .|.|.|.|      |.|.:. :|..
Mosquito   471 TSQGNISILNYAPVTDQDFGTLTCWAVNEVGP--------QSQPCTFQLVLADLPSPVSNCSLPN 527

  Fly   367 TTTTAAEI-ALDGY 379
            .|...||| ...||
Mosquito   528 RTQQFAEIQCTPGY 541

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	24/142 (17%)
		Ig	69..139	CDD:143165	17/111 (15%)
		IG_like	165..249	CDD:214653	20/88 (23%)
		IGc2	172..237	CDD:197706	18/67 (27%)
		IG_like	267..348	CDD:214653	20/85 (24%)
		Ig	270..339	CDD:299845	18/73 (25%)
AgaP_AGAP009596	XP_318623.4	V-set	12..118	CDD:284989
		IG_like	12..101	CDD:214653
		Ig	146..209	CDD:299845	12/40 (30%)
		Ig	234..308	CDD:299845	10/73 (14%)
		IG_like	247..310	CDD:214653	6/62 (10%)
		IGc2	343..408	CDD:197706	18/68 (26%)
		IG_like	431..508	CDD:214653	22/94 (23%)
		ig	431..504	CDD:278476	20/90 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910