DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-epsilon and AgaP_AGAP005794

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_315806.4	Gene:	AgaP_AGAP005794 / 1276459	VectorBaseID:	AGAP005794	Length:	421	Species:	Anopheles gambiae

Alignment Length:	242	Identity:	62/242 - (25%)
Similarity:	100/242 - (41%)	Gaps:	27/242 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 FLYVGLGCLIASSVALSTDTGSEGNAGNVGGSTLNNVISEDPEFTDVIENITVPAGRNVKLACSV 75
            ||:.....|:.||..|:....::....|..|...:..|:::.  |.||..    .|....|.|||
Mosquito    52 FLFSQPPYLLFSSFPLADSNEAKAAHRNSLGPLQSQFITKNN--TRVISQ----RGGLAVLPCSV 110

  Fly    76 KNLGSYKVAWMHFEQSAILTVHNHVITRNPRISVTHDKHDKHRTWFLHINNVQEEDRGRYMCQIN 140
            .......|:|...:...:|||.....:.:.|..|.|.:|  ...|.|.|.|.::||.|.|.|||:
Mosquito   111 TMTTPATVSWFRRKDYQLLTVGLSTYSSDDRFLVEHTRH--LGNWALRIKNARKEDEGLYECQIS 173

  Fly   141 TVTAKTQYGFVKVVVPPNIDDALTSSDIIVREGDNVTLRCKAKGSPEP-----------TIKWKR 194
              |...|..|:::.:...:.:.|.:.|:.:.||..:.|.||.|.:.|.           .:.:.:
Mosquito   174 --THPPQSIFIELRIVEAVAEILEAPDLHIDEGSTLRLECKLKRATESPLYVFWYHEDRMVNYDQ 236

  Fly   195 DDGNKIVINKTLEVHDLETDSLELERISRLHMGAYLCIASNGVPPSV 241
            :||..:..||      |.:..|.:...:..|.|.|.|..:|....||
Mosquito   237 EDGVSVSNNK------LTSSILTVRNATARHGGNYTCAPANARQSSV 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	28/95 (29%)
		Ig	69..139	CDD:143165	22/69 (32%)
		IG_like	165..249	CDD:214653	21/88 (24%)
		IGc2	172..237	CDD:197706	18/75 (24%)
		IG_like	267..348	CDD:214653
		Ig	270..339	CDD:299845
AgaP_AGAP005794	XP_315806.4	Ig	92..179	CDD:299845	29/96 (30%)
		IG_like	99..173	CDD:214653	24/79 (30%)
		IG_like	197..281	CDD:214653	21/87 (24%)
		ig	203..267	CDD:278476	16/69 (23%)
		CCC1_like	<305..362	CDD:294198
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810