DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-epsilon and AgaP_AGAP010542

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_314509.4	Gene:	AgaP_AGAP010542 / 1275271	VectorBaseID:	AGAP010542	Length:	168	Species:	Anopheles gambiae

Alignment Length:	144	Identity:	47/144 - (32%)
Similarity:	66/144 - (45%)	Gaps:	9/144 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 YVGLGCLIASSVA-LSTDTGSEGNAGNVGGSTLNNVISEDPEFTDVI-ENITVPAGRNVKLACSV 75
            |.|....:.:|.| |.|...|....|....|..     |:|.|.|.. .|:|...|::..|:|.|
Mosquito    32 YDGYKSFLDTSTAHLRTYVASGSTPGQTSQSKW-----EEPYFDDTTPRNVTGLVGKSAYLSCRV 91

  Fly    76 KNLGSYKVAWMHFEQSAILTVHNHVITRNPRISVTHDKHDKHRTWFLHINNVQEEDRGRYMCQIN 140
            ||||:..|:|:......||||.::..|.:.|...||  |.....|.|.|...|:.|.|.|.|||:
Mosquito    92 KNLGNKTVSWIRHRDIHILTVGSYTYTSDQRFQATH--HKDVDDWTLQIKWAQKRDAGIYECQIS 154

  Fly   141 TVTAKTQYGFVKVV 154
            |...::.:..:.||
Mosquito   155 TQPVRSYFVTLSVV 168

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	34/96 (35%)
		Ig	69..139	CDD:143165	26/69 (38%)
		IG_like	165..249	CDD:214653
		IGc2	172..237	CDD:197706
		IG_like	267..348	CDD:214653
		Ig	270..339	CDD:299845
AgaP_AGAP010542	XP_314509.4	V-set	72..168	CDD:284989	32/97 (33%)
AgaP_AGAP010542	XP_314509.4	IG_like	74..167	CDD:214653	32/94 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810