DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-epsilon and AgaP_AGAP005068

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_313942.4	Gene:	AgaP_AGAP005068 / 1274750	VectorBaseID:	AGAP005068	Length:	305	Species:	Anopheles gambiae

Alignment Length:	209	Identity:	57/209 - (27%)
Similarity:	85/209 - (40%)	Gaps:	29/209 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 DVIENITVPAGRNVKLACSVKNLGSYKVAWMHFEQSAILTVHNHVITRNPRISVTHDKHDKHRTW 120
            ||..|:||..|:...|.|.|:.||...|||:......|||:.....|.:.|..|...:...:  |
Mosquito    18 DVPRNLTVTVGQTGFLHCRVERLGDQDVAWIRQRDLHILTMGASTYTSDQRFQVIRPEGSVN--W 80

  Fly   121 FLHINNVQEEDRGRYMCQINTVTAKTQYGFVKVVVPPNIDDALTSSDIIVREGDNVTLRCKAKGS 185
            .|.|...|..|.|.|.||||| ..|....:|..|:.... ..|..|||.::.|..:|:.|..:..
Mosquito    81 TLQIKYPQTRDSGVYECQINT-EPKMSLSYVLNVIELRA-RILGPSDIFIKSGSEITMVCVIQQG 143

  Fly   186 PEP--TIKWKR---------------DDGNKIVINKTLEVHDLETDSLELERISRLHMGAYLCIA 233
            |..  |:.|.:               .|..:|.|.  .:..|..|..|:::|..:...|.|.|:
Mosquito   144 PHELGTVFWYKGRYCQPLAQENDIHSGDRGRITIE--TDWTDALTSRLKIKRAIQGDTGNYTCV- 205

  Fly   234 SNGVPPSVSKRIKV 247
                 |::::...|
Mosquito   206 -----PTMARSASV 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	32/95 (34%)
		Ig	69..139	CDD:143165	22/69 (32%)
		IG_like	165..249	CDD:214653	21/100 (21%)
		IGc2	172..237	CDD:197706	16/81 (20%)
		IG_like	267..348	CDD:214653
		Ig	270..339	CDD:299845
AgaP_AGAP005068	XP_313942.4	IG_like	20..113	CDD:214653	32/95 (34%)
		Ig	23..99	CDD:299845	25/77 (32%)
		Ig	134..205	CDD:143165	14/72 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810