DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-epsilon and AgaP_AGAP002707

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_312221.5	Gene:	AgaP_AGAP002707 / 1273261	VectorBaseID:	AGAP002707	Length:	499	Species:	Anopheles gambiae

Alignment Length:	268	Identity:	62/268 - (23%)
Similarity:	98/268 - (36%)	Gaps:	84/268 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 PEFTDVIENITVPAGRNVK--------LACSVKNLGSYKVAWMH--FEQSAILTVHNHVITRNPR 106
            |.|.:.: |:|..|...|.        |.|.|..|....|.|:.  .::.::|||.|:..:.:||
Mosquito   197 PFFEEPV-NVTSGAALQVGYHLSTEAILNCRVGMLKDKTVMWIRRTTDKVSLLTVGNNTYSGDPR 260

  Fly   107 ISVTHDKHDKHRTWFLHINNVQEEDRGRYMCQINTVTAKTQYGFVKVVVPP-NIDDAL--TSSDI 168
            |.|   |......|.||||.::.:|.|.||||::|...:.....:.|:.|. .|.|.:  ..||.
Mosquito   261 IKV---KFQYPNNWRLHINPIKSDDAGLYMCQVSTHPPRVFATNLTVLEPAVRIVDEMGYEFSDR 322

  Fly   169 IVREGDNVTLRCKAKGS------PEPT---------------------------IKWKRDDGNKI 200
            ..:.|..:.:.|:...|      |.|.                           .|..:|| ||:
Mosquito   323 YYKLGSTIEISCQVSTSYLATLPPSPKSAGQQQRSKTSPVGASANALDETAKTGSKATKDD-NKL 386

  Fly   201 -------VINKTLEVHDLETD--------------SLELERISRLHMGAYLCIAS---------- 234
                   :|:.|.:..:|..|              .|.:.:.:|:|.|.|.|..:
Mosquito   387 SDSTERGLISWTKDGAELPKDVKMSFSGTKQWLISRLSILQANRVHNGVYNCTVAGKQSQAAQVQ 451

  Fly   235 --NGVPPS 240
              ||..|:
Mosquito   452 VLNGETPA 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	32/105 (30%)
		Ig	69..139	CDD:143165	26/79 (33%)
		IG_like	165..249	CDD:214653	25/142 (18%)
		IGc2	172..237	CDD:197706	21/130 (16%)
		IG_like	267..348	CDD:214653
		Ig	270..339	CDD:299845
AgaP_AGAP002707	XP_312221.5	IG_like	221..304	CDD:214653	27/85 (32%)
		Ig	<237..305	CDD:299845	22/70 (31%)
		Ig	<395..443	CDD:299845	10/47 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810