DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-epsilon and CNTN1

DIOPT Version :9

Sequence 1:NP_001137799.1 Gene:DIP-epsilon / 7354433 FlyBaseID:FBgn0259714 Length:467 Species:Drosophila melanogaster
Sequence 2:NP_001834.2 Gene:CNTN1 / 1272 HGNCID:2171 Length:1018 Species:Homo sapiens


Alignment Length:388 Identity:86/388 - (22%)
Similarity:141/388 - (36%) Gaps:106/388 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   122 LHINNV-QEEDRGRYMCQINTVTAKTQYGFVKVV-----------VPPNIDDALTSSDIIVREGD 174
            |.|||. :::|.|.|.|     .|...||.|:..           .||.     ...::.|:||.
Human    98 LVINNPDKQKDAGIYYC-----LASNNYGMVRSTEATLSF
GYLDPFPPE-----ERPEVRVKEGK 152

  Fly   175 NVTLRCKAKGSPEPTIKWKRDDGNKIVINK-----TLEVHDLETD---SLELERISRLHMGAYLC 231
            .:.|.|      :|...:..|...:.::|:     |::.....:.   :|.:..:.....|.|.|
Human   153 GMVLLC------DPPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSC 211

  Fly   232 IASNGVPPSVSKRIKVSVDFSPMVWIPHQL--------------VGIPIGFNITLECFIEANPTS 282
            ..|:   ||::|  .|...|.|::.||.:.              |...:|.|:|||||...||..
Human   212 FVSS---PSITK--SVFSKFIPLI
PIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVP 271

  Fly   283 LNYWTRENDQMITESSKYKTETIPGHPSYKATMRLTITNVQSSDYGNYKCVAKNPRGDMDGNIKL 347
            ...|.:..:.|.:.:....:..:           |.|.|:|..|.|.|:|.|:|.||......::
Human   272 DIRWRKVLEPMPSTAEISTSGAV-----------LKIFNIQLEDEGIYECEAENIRGKDKHQARI 325

  Fly   348 YMSSPP-----------------------TTQPPPTTTTLRR-TTTTAAEIALDGYINTPLNGNG 388
            |:.:.|                       |.:|.||...|:. ......|:.|  |..|..|...
Human   326 YVQAFPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNGYAYHKGELRL--YDVTFENAGM 388

  Fly   389 IGIVGEGPTNSVIASGKSSIKYLSNLNEIDKSKQKLTGS---------SPKG-----FDWSKG 437
            ...:.|....::.|:.:..|..|:...|::..|:|:..:         .||.     |.||||
Human   389 YQCIAENTYGAIYANAELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKG 451

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-epsilonNP_001137799.1 IG_like 59..155 CDD:214653 12/44 (27%)
Ig 69..139 CDD:143165 8/17 (47%)
IG_like 165..249 CDD:214653 18/91 (20%)
IGc2 172..237 CDD:197706 13/72 (18%)
IG_like 267..348 CDD:214653 23/80 (29%)
Ig 270..339 CDD:299845 19/68 (28%)
CNTN1NP_001834.2 Ig1_Contactin-1 40..132 CDD:143257 12/38 (32%)
I-set 41..130 CDD:254352 12/36 (33%)
Ig2_Contactin-2-like 134..230 CDD:143204 22/111 (20%)
IG_like 144..221 CDD:214653 17/87 (20%)
Ig3_Contactin-1 241..328 CDD:143259 25/97 (26%)
IG_like 249..327 CDD:214653 24/88 (27%)
I-set 331..408 CDD:254352 13/78 (17%)
Ig 332..408 CDD:299845 12/77 (16%)
IG_like 422..501 CDD:214653 8/30 (27%)
Ig5_Contactin-1 429..501 CDD:143260 7/23 (30%)
IG_like 511..600 CDD:214653
Ig6_Contactin_like 520..601 CDD:143171
FN3 610..697 CDD:238020
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 693..717
FN3 709..801 CDD:238020
fn3 811..893 CDD:278470
FN3 905..989 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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