DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-epsilon and AgaP_AGAP011128

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_309518.4	Gene:	AgaP_AGAP011128 / 1270797	VectorBaseID:	AGAP011128	Length:	269	Species:	Anopheles gambiae

Alignment Length:	248	Identity:	70/248 - (28%)
Similarity:	106/248 - (42%)	Gaps:	45/248 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 IASSVALS-TDTGSEGNAG-NVGGSTLNNVISEDPEFTDVIENITVPAGRNVKLACSVKNLGSYK 82
            |::|:||| .::|:...|| .:.||.              :.|:|...|.:..|.|.||.||:..
Mosquito     3 ISTSLALSKLNSGATFFAGPYLDGSG--------------VSNVTTQIGTHAYLPCKVKQLGNKS 53

  Fly    83 VAWMHFEQSAILTVHNHVITRNPRISVTHDKHDKHRTWFLHINNVQEEDRGRYMCQINT---VTA 144
            |:|:......||||.......:.|....:  .:....|.|.|..||..|.|.|.||::|   ::|
Mosquito    54 VSWVRVRDDHILTVDRMTFIADERFQSFY--VESSGVWTLQIKYVQARDAGIYECQVSTEPKISA 116

  Fly   145 KTQYGFVKVVVPPNIDDALTSSDIIVREGDNVTLRCKAKGSPEPT--IKWKRDDGNKIVINKTLE 207
            :..   :.||||..  :.:..||..|:.|..|.|||..:|:.||.  |.|..  |.:.:..::..
Mosquito   117 RVH---LHVVVPRT--ELIGDSDRYVKAGSAVILRCVVRGALEPPSYIIWYH--GTQQIFTESRR 174

  Fly   208 ---------VHDLETD------SLELERISRLHMGAYLCIASNGVPPSVSKRI 245
                     ..||:.|      ||.:|...:...|.|.|..||..|.:||..:
Mosquito   175 GWKTQLDRGAPDLDGDIHSTIGSLIIESTRKKDSGNYSCSPSNSPPITVSLHV 227

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	29/98 (30%)
		Ig	69..139	CDD:143165	22/69 (32%)
		IG_like	165..249	CDD:214653	28/98 (29%)
		IGc2	172..237	CDD:197706	22/81 (27%)
		IG_like	267..348	CDD:214653
		Ig	270..339	CDD:299845
AgaP_AGAP011128	XP_309518.4	IG_like	30..122	CDD:214653	28/96 (29%)
		Ig	32..123	CDD:299845	27/95 (28%)
		IG_like	133..227	CDD:214653	28/95 (29%)
		IGc2	140..218	CDD:197706	21/79 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810