DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-epsilon and Cd86

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_006521804.1	Gene:	Cd86 / 12524	MGIID:	101773	Length:	314	Species:	Mus musculus

Alignment Length:	348	Identity:	69/348 - (19%)
Similarity:	109/348 - (31%)	Gaps:	122/348 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 VGLGCLIASSVALSTDTGSEGNAGNVGGSTLNNVISEDPEFTDVIENITVPAGRNVKLACSVKNL 78
            :||..||..:|.|.:|..|........|:.....     .||.. :||               :|
Mouse    12 MGLAILIFVTVLLISDAVSVETQAYFNGTAYLPC-----PFTKA-QNI---------------SL 55

  Fly    79 GSYKVAWMHFEQSAILTVHNHVITRNPRISVT-----HDKHDKHRTWFLHINNVQEEDRGRYMCQ 138
            ....|.|...::   |.::.|.:......||.     ....|:: .|.|.::|||.:|.|.|.|.
Mouse    56 SELVVFWQDQQK---LVLYEHYLGTEKLDSVNAKYLGRTSFDRN-NWTLRLHNVQIKDMGSYDCF 116

  Fly   139 INTVTAKTQYGFVKVVVPPN----IDDALTSSDII-------VREGDNVT------LRCKAK-GS 185
            |..             .||.    :...||...:|       ::...|||      |.|.:| |.
Mouse   117 IQK-------------KPPTGSIILQQTLTELSVIANFSEPEIKLAQNVTGNSGINLTCTSKQGH 168

  Fly   186 PEPTIKWKRDDGNKIVINKTLEVHDLETDSLELERISRLHMGAYLCIASNGVPPSVSKRIKVSVD 250
            |:|...:      .::.|.|.|                  .|..:.|:.:.|....|....:|:.
Mouse   169 PKPKKMY------FLITNSTNE------------------YGDNMQISQDNVTELFSISNSLSLS 209

  Fly   251 FSPMVWIPHQLVGIPIGFNITLECFIEAN---------------PTSLNYWTRENDQMITESSK- 299
            |...||            ::|:.|.:|..               |:...|| :|....:|.:..
Mouse   210 FPDGVW------------HMTVVCVLETESMKISSKPLNFTQEFPSPQTYW-KEITASVTVALLL 261

  Fly   300 --------YKTETIPGHPSYKAT 314
                    :|....|..||..|:
Mouse   262 VMLLIIVCHKKPNQPSRPSNTAS 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	20/100 (20%)
		Ig	69..139	CDD:143165	17/74 (23%)
		IG_like	165..249	CDD:214653	17/97 (18%)
		IGc2	172..237	CDD:197706	14/71 (20%)
		IG_like	267..348	CDD:214653	13/72 (18%)
		Ig	270..339	CDD:299845	13/69 (19%)
Cd86	XP_006521804.1	IgV_CD86	33..138	CDD:319336	27/142 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910