DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DIP-epsilon and BTNL3

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_932079.1	Gene:	BTNL3 / 10917	HGNCID:	1143	Length:	466	Species:	Homo sapiens

Alignment Length:	386	Identity:	78/386 - (20%)
Similarity:	122/386 - (31%)	Gaps:	151/386 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   122 LHINNVQEEDRGRYMC----QINTVTAKTQYGFVKVVVPPNIDDALTSSDIIVREG---DNVTLR 179
            |.:.|:...|.|.|.|    ||....|..:   ::|.       ||.|..:|...|   ..:.|.
Human    99 LRLKNITPSDIGLYGCWFSSQIYDEEATWE---LRVA-------ALGSLPLISIVGYVDGGIQLL 153

  Fly   180 CKAKG-SPEPTIKWKRDDGNKIVINKTLEVHDLETDS-----------LELERISRLHMGAYLC- 231
            |.:.| .|:||.|||...|           .||.:||           :|:..|.:.:.|:.||
Human   154 CLSSGWFPQPTAKWKGPQG-----------QDLSSDSRANADGYSLYDVEISIIVQENAGSILCS 207

  Fly   232 --IASNGVPPSVSKRIKV-SVDFSPMVW---------IPHQLVGIPIGFNITLECFIEAN---PT 281
              :|...  ..|..::.: ...|.|..|         :...|.|:.:|..|.   |.::.   ..
Human   208 IHLAEQS--HEVESKVLIGETFFQPSPWRLASILLGLLCGALCGVVMGMIIV---FFKSKGKIQA 267

  Fly   282 SLNYWTRENDQM-ITESSKYKTETI----PGHP---------------------SYKATMRLTIT 320
            .|: |.|::.|. :.::.|:..|..    ..||                     |.|...|.::.
Human   268 ELD-WRRKHGQAELRDARKHAVEVTLDPETAHPKLCVSDLKTVTHRKAPQEVPHSEKRFTRKSVV 331

  Fly   321 NVQSSDYGNYKC---VAKNP-------RGDMD---GNIKL-----------------------YM 349
            ..|....|.:..   |.:|.       |.|:|   .|:.|                       ::
Human   332 ASQGFQAGKHYWEVDVGQNVGWYVGVCRDDVDRGKNNVTLSPNNGYWVLRLTTEHLYFTFNPHFI 396

  Fly   350 SSPPTTQPPPTTTTLRRTTTTAAEIALDGYINTPLNGNGIGIVGEGPTNSVIASGKSSIKY 410
            |.||:|  |||..                         |:.:..||.|.|...:...|:.|
Human   397 SLPPST--PPTRV-------------------------GVFLDYEGGTISFFNTNDQSLIY 430

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	10/36 (28%)
		Ig	69..139	CDD:143165	6/20 (30%)
		IG_like	165..249	CDD:214653	24/102 (24%)
		IGc2	172..237	CDD:197706	21/82 (26%)
		IG_like	267..348	CDD:214653	23/145 (16%)
		Ig	270..339	CDD:299845	17/107 (16%)
BTNL3	NP_932079.1	Ig_MOG_like	33..132	CDD:319291	9/35 (26%)
BTNL3	NP_932079.1	SPRY_PRY_C-I_1	289..461	CDD:293968	29/169 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910