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Protein Alignment DIP-epsilon and CHL1

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_006605.2	Gene:	CHL1 / 10752	HGNCID:	1939	Length:	1224	Species:	Homo sapiens

Alignment Length:	354	Identity:	80/354 - (22%)
Similarity:	134/354 - (37%)	Gaps:	61/354 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LIASSVALSTDTGSEGNAGNVGGSTLNNVISEDPEF------TDVIENITVPAGRNVKLACSVKN 77
            |..:|:..:.|:.|....    ||..|::....|:.      :....:||:..|..:.|.|..:.
Human   222 LTVNSLKHANDSSSSTEI----GSKANSIKQRKPKLLLPPTESGSESSITILKGEILLLECFAEG 282

  Fly    78 LGSYKVAWMHFEQSAILTVHNHVITRNPRISVTHDKHDKHRTWFLHINNVQEEDRGRYMCQINTV 142
            |.:.:|.|            |.:....|:...|.:.:.|    .|.|.||..:|:|.|.|..:..
Human   283 LPTPQVDW------------NKIGGDLPKGRETKENYGK----TLKIENVSYQDKGNYRCTASNF 331

  Fly   143 TAKTQYGF-VKVVVPPNIDDALTSSDIIVREGDNVTLRCKAKGSPEPTIKWKRDDGNKIVINKTL 206
            .....:.| |.|..||.......|:  :...|.|..|.|:|:|.|:|||||:       |....:
Human   332 LGTATHDFHVIVEEPPRWTKKPQSA--VYSTGSNGILLCEAEGEPQPTIKWR-------VNGSPV 387

  Fly   207 EVHDLETD-----SLELERISRLHMGAYLCIASNGVPPSVSKRIKVS-VDFSPMVWIPH-QLVGI 264
            :.|....|     .:....:...|...|.|.||| |..::.....:. ||..|::.... :....
Human   388 DNHPFAGDVVFPREISFTNLQPNHTAVYQCEASN-VHGTILANANIDVVDVRPLIQTKDGENYAT 451

  Fly   265 PIGFNITLECFIEANPTSLNYWTRENDQMITESSKYKTETIPGHPSYKATMRLTITNVQSSDYGN 329
            .:|::..|.|...|:|.::..|.:..:....|..:|       |.....|:::..|.  ..|.|:
Human   452 VVGYSAFLHCEFFASPEAVVSWQKVEEVKPLEGRRY-------HIYENGTLQINRTT--EEDAGS 507

  Fly   330 YKCVAKNPRG--------DMDGNIKLYMS 350
            |.|..:|..|        |:....||.:|
Human   508 YSCWVENAIGKTAVTANLDIRNATKLRVS 536

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.