DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-epsilon and LOC103908669

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_021325224.1	Gene:	LOC103908669 / 103908669	-ID:	-	Length:	918	Species:	Danio rerio

Alignment Length:	427	Identity:	97/427 - (22%)
Similarity:	147/427 - (34%)	Gaps:	118/427 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 ENITVPAGRNVKLACSVKNL-GSYKVAWMHFEQSAILTVHNHVITRNPRISVTHDKHDKHR---- 118
            :::||..|..|.|...:..| |...:.|....:..:|...:..|...|....  |:..|.|
Zfish   136 KSLTVTEGYPVILHTGITKLHGDELIVWRFGVEGKLLAKEDKEIKSPPYYDT--DERFKGRLKLN 198

  Fly   119 --TWFLHINNVQEEDRGRYMCQINTVTAKTQYGFVKVVVPPNIDDALTSSDII------------ 169
              |..|.|||:::.|.|.|..:||.....|...|...|....:..|..:..||
Zfish   199 DQTGSLTINNMKDTDAGLYTVKINNNKLTTYRDFTVTVSGSGLTSAAVAGIIIGLLMLFAVVAGS 263

  Fly   170 ---------------------VREGDNVTLRCKAKGSPEPTIKWKRDDGNKIV------INKT-- 205
                                 ..|.:||||:.|.|......|:|...:.|.::      |.:|
Zfish   264 GFLYHRRMIAEQQKHMVKKIHTAERENVTLKTKTKLLEGDEIQWWFSNENFLIAEIIEGIGETYD 328

  Fly   206 ---------LEVHDLETDSLELERISRLHMGAYLCIASNGVPPSVSKRIKVSVDFSPMVWIPHQL 261
                     ||: |.:|.||.::.|.|.|.|.|..        .:.||.:.:.:|:..|:|..:.
Zfish   329 GLDGRFSDILEL-DKKTGSLNIKNIRRKHTGDYRL--------KIIKRSRETSNFNFSVYIKEEK 384

  Fly   262 VGIPIGFNITLECFIEANPTSLNYWT--RENDQMITESSKYKTETIPGHPSYKATMR-------L 317
            :.:..|.::||:...|........|.  .|||.:...:...:..|.|.. .::.|::       |
Zfish   385 MIVSCGESVTLKADAEIQREDEVQWLFHIENDLIAKMTGNTREITYPDE-RFRDTLKMDEKTGSL 448

  Fly   318 TITNVQSSDYGNYKCVAKNPRGDMDGNIKLYMSSPPTTQPPPTTTTLRRTTTTAAEIALDGYINT 382
            ||.|:.....|.|| |....||:                     .|.:..|.         |||.
Zfish   449 TINNIGDEHTGLYK-VKVISRGE---------------------ATYKTFTV---------YINA 482

  Fly   383 PLNGNGI--GIVGEGPTNSVIASGKSSIKYLSNLNEI 417
            .:|...|  |.:||..|.      |..||...| |||
Zfish   483 LINEKFIFDGRIGESVTL------KPYIKIQRN-NEI 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	26/102 (25%)
		Ig	69..139	CDD:143165	19/76 (25%)
		IG_like	165..249	CDD:214653	27/133 (20%)
		IGc2	172..237	CDD:197706	23/81 (28%)
		IG_like	267..348	CDD:214653	21/89 (24%)
		Ig	270..339	CDD:299845	18/77 (23%)
LOC103908669	XP_021325224.1	Ig	31..121	CDD:325142
		Ig	140..236	CDD:325142	25/97 (26%)
		Ig_CD2_like_N	285..381	CDD:319316	27/104 (26%)
		Ig	390..480	CDD:325142	23/121 (19%)
		Ig	495..585	CDD:325142	10/25 (40%)
		Ig	608..684	CDD:325142
		Ig	692..777	CDD:325142
		Ig	805..883	CDD:325142
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910