DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-epsilon and LOC101883645

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_021325225.1	Gene:	LOC101883645 / 101883645	-ID:	-	Length:	639	Species:	Danio rerio

Alignment Length:	375	Identity:	75/375 - (20%)
Similarity:	143/375 - (38%)	Gaps:	106/375 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   124 INNVQEEDRGRYMCQINTVTAKTQYGFVKVVVPPNIDDALT------------SSDII----VRE 172
            :|..:||:......:.|| :.:|:       :..|:|..|.            |:|.:    |.|
Zfish    11 LNEKEEEEEEEEGAKRNT-SKRTE-------IHSNMDYVLRTVMFALVICGVFSADEVKVKSVME 67

  Fly   173 GDNVTLRCKAKGSPEPT-------IKW---KRDDG------NKIVINKTLEVHDLETDSLELERI 221
            ||:|||      :|:.|       |||   |:...      |..::...||.:|| |.||.:..:
Zfish    68 GDSVTL------NPDITQIQRINQIKWMFQKKGSNAAENIRNVEILQGRLEKNDL-TGSLTINNM 125

  Fly   222 SRLHMGAYLCIA--SNGVPPSVSKRIKVSVDFSPMVWIPH----QLVGIPIGFNITLECFI-EAN 279
            ...|.|.|....  .||   :.:....|:|:..|.|...|    :::.:..|..:.||..: |.:
Zfish   126 RTKHSGLYTLEIDHDNG---TNNASFNVTVNEVPSVIEAHKAEIKILTVKKGEPLFLETDVTEFH 187

  Fly   280 PTSLNYWTRENDQMITESSKYKTETIPGHPS---YKATMR-------LTITNVQSSDYGNYKC-V 333
            ...|..|...::..:......:|::.|.:.:   ||..::       ||:..::.:|.|.|.. :
Zfish   188 GDELIVWRFGDEGKLLAKEDKETKSSPYYNADERYKGRLQLNDQTGFLTLDKMKDTDAGYYTVRI 252

  Fly   334 AKNPRGDMDGNIKLYMSSPPTTQPPPTTTTLRRTTTTAAEIALDGYINTPLNGNGIGIVGEGPTN 398
            :.|.:                       ||.::.........:.|.:.:|..|..|.::
Zfish   253 SSNKQ-----------------------TTYKKFAVNFTGFIISGSVVSPSAGAIIALL------ 288

  Fly   399 SVIA--SGKSSIKYLSNLNEIDKSKQKLTGSSPKGFDWSKGKSSGSHGNL 446
            .|||  :|...:.|...::|:   ::.:.|:    ..:::|:|...|..|
Zfish   289 LVIAVVAGLGVLYYRRKISEL---QEHVVGT----LKFTEGESVYLHTGL 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	6/30 (20%)
		Ig	69..139	CDD:143165	3/14 (21%)
		IG_like	165..249	CDD:214653	29/105 (28%)
		IGc2	172..237	CDD:197706	24/82 (29%)
		IG_like	267..348	CDD:214653	16/92 (17%)
		Ig	270..339	CDD:299845	15/80 (19%)
LOC101883645	XP_021325225.1	Ig	67..152	CDD:325142	26/94 (28%)
		Ig	174..263	CDD:325142	18/111 (16%)
		Ig	320..418	CDD:325142	4/12 (33%)
		Ig	427..517	CDD:325142
		Ig	530..621	CDD:325142
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910