DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-epsilon and LOC101732679

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_017945096.1	Gene:	LOC101732679 / 101732679	-ID:	-	Length:	324	Species:	Xenopus tropicalis

Alignment Length:	285	Identity:	54/285 - (18%)
Similarity:	99/285 - (34%)	Gaps:	108/285 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 NITVPAGRNVKLACSV---KNLGSYKVAWMHFEQSAILTVHNHVITRNPRISVTHDKHDKH---- 117
            ::....|.:|.|.||:   .|..:.::.|..             ||..|.:.:..:..|.:
Frog    34 SVVATLGSDVLLPCSLTPEMNAENMEIRWFK-------------ITYQPYVHLYINGKDDYTAQM 85

  Fly   118 -----RT-----------WFLHINNVQEEDRGRYMCQINTVTAKTQYGFVKVVVPPNIDDALTSS 166
                 ||           :.|.|..|..:|.|.|.|.:.:    |::..|..|   .:......|
Frog    86 PQFANRTELLKENITRGIFLLRIRKVTAQDSGNYYCFVES----TEHHGVATV---QLQVTAVGS 143

  Fly   167 DIIVREGDNVTLRCKAKG-SPEPTIKWKRDDGNKIVINKTLEVHDLETDSLELERISRLHMGAYL 230
            .:::......|:.|::.| .|||.:.|..::|||::.:              :|::.:.....|.
Frog   144 PLVISVITEDTVFCESDGWYPEPYLIWTDNEGNKVIPS--------------MEKVLKDEKSLYH 194

  Fly   231 CIASNGVPPSVSKRIKVSVDFSPMVWIPHQLVGIPIGFNITLECFIEANPTSLNYWTRENDQMIT 295
            .:::..:||:.|                          |||  |.:.   :|||
Frog   195 ILSAIYLPPTSS--------------------------NIT--CTVS---SSLN----------- 217

  Fly   296 ESSKYKTETIPGHPSYKATMRLTIT 320
            :|.:..|:||        .|||.:|
Frog   218 QSKQSSTQTI--------EMRLPVT 234

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	22/117 (19%)
		Ig	69..139	CDD:143165	19/92 (21%)
		IG_like	165..249	CDD:214653	16/84 (19%)
		IGc2	172..237	CDD:197706	12/65 (18%)
		IG_like	267..348	CDD:214653	15/54 (28%)
		Ig	270..339	CDD:299845	14/51 (27%)
LOC101732679	XP_017945096.1	Ig	27..139	CDD:416386	23/124 (19%)
		FR1	27..49	CDD:409353	4/14 (29%)
		Ig strand A	28..33	CDD:409353
		Ig strand A'	35..38	CDD:409353	0/2 (0%)
		Ig strand B	41..49	CDD:409353	3/7 (43%)
		CDR1	50..58	CDD:409353	1/7 (14%)
		Ig strand C	58..63	CDD:409353	0/4 (0%)
		FR2	59..63	CDD:409353	0/3 (0%)
		CDR2	64..82	CDD:409353	4/30 (13%)
		Ig strand C'	68..76	CDD:409353	1/7 (14%)
		Ig strand C'	77..80	CDD:409353	0/2 (0%)
		FR3	84..124	CDD:409353	9/39 (23%)
		Ig strand D	91..96	CDD:409353	2/4 (50%)
		Ig strand E	102..110	CDD:409353	2/7 (29%)
		Ig strand F	117..125	CDD:409353	3/7 (43%)
		CDR3	125..127	CDD:409353	0/5 (0%)
		Ig strand G	127..139	CDD:409353	2/14 (14%)
		FR4	128..139	CDD:409353	2/13 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910