DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DIP-epsilon and LOC100536726

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_021325232.1	Gene:	LOC100536726 / 100536726	-ID:	-	Length:	1328	Species:	Danio rerio

Alignment Length:	446	Identity:	100/446 - (22%)
Similarity:	164/446 - (36%)	Gaps:	112/446 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 NVGGSTLN---NV-ISEDPEFTDVIENITVPAGRNVKLACSVKNLGSYKVAWMHFEQSAILTVHN 98
            |..|.|:|   :| |.|:       |.:.|..|.:|.|....:.....:|.|:...|:.::.
Zfish   364 NCSGETINWRFSVHIKEE-------EKMLVSPGESVTLKADAEIQREDEVQWLFKVQNDLIA--- 418

  Fly    99 HVITRNPRISVTHD-------KHDKHRTWFLHINNVQEEDRGRYMCQINT---VTAKTQYGFVKV 153
             .:|.|.|..:..|       |.|| :|.||.|||::.|..|.|..:||:   .|.||...::
Zfish   419 -KMTGNTREIIYPDERFRDTLKMDK-KTGFLTINNIEPEHTGLYKLKINSRGEATYKTFSVYI-- 479

  Fly   154 VVPPNIDDALTSSDIIV--REGDNVTLRCKAKGSPEPTIKWKRDDGNKIVINKT-----LEVHD- 210
                   :|||:..:|.  |.|::|||:...|......|:|...|.::::...|     :..||
Zfish   480 -------NALTNEKLIFEGRIGESVTLKPDIKIQRNNEIQWMIADQDRLIAKMTRGARKITYHDE 537

  Fly   211 -----LE----TDSLELERISRLHMGAY--LCIASNGVPPSVSKRIKVSVDFSPMVWIPHQLVGI 264
                 ||    |.||.:..|:...:..|  ..|:|:|   :..|:.:|.:.            |.
Zfish   538 RFRDRLELNKKTGSLTINNITIKDIREYKMKIISSSG---TTEKKFRVLIK------------GD 587

  Fly   265 PIGFN----ITLECFIEANPTSLNYWTRENDQMITE------------SSKYKTETIPGHPSYKA 313
            |:.||    ..|:|..:.....:.:..:..:..|.|            ..:::    .|....:.
Zfish   588 PVFFNEGDRAVLQCAADIQTDKIEWRFKSEESPIAEVEGGQIFLYNGSDMRFR----DGLEVDER 648

  Fly   314 TMRLTITNVQSSDYGNYKCVAK-NPRGDMDGNIKLYMSSPPTTQPPPTTTTLRRTTTTAAEIALD 377
            |..|.|.|.:....|.|:.:.| :..||......|::.............||:..|.......:.
Zfish   649 TGSLIIKNFRHEHVGLYQLMKKSSSTGDSVKAFNLFVREKKINTAERENVTLKTETKLLEGDEIQ 713

  Fly   378 GYINTPLNGN--------GIGIVGEGPTNSVIASGKSSIKYLSNLNEIDKSKQKLT 425
            .:.:   |.|        |||....||.           |..|:..|:||....||
Zfish   714 WWFS---NENFLIAEIIEGIGETYSGPK-----------KRFSDCLELDKETGSLT 755

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	29/105 (28%)
		Ig	69..139	CDD:143165	21/76 (28%)
		IG_like	165..249	CDD:214653	25/102 (25%)
		IGc2	172..237	CDD:197706	20/81 (25%)
		IG_like	267..348	CDD:214653	16/97 (16%)
		Ig	270..339	CDD:299845	12/81 (15%)
LOC100536726	XP_021325232.1	Ig	32..123	CDD:325142
		Ig	141..237	CDD:325142
		Ig_CD2_like_N	284..379	CDD:319316	5/14 (36%)
		Ig	389..479	CDD:325142	27/94 (29%)
		Ig	494..585	CDD:325142	23/93 (25%)
		Ig	608..685	CDD:325142	13/80 (16%)
		Ig_CD2_like_N	692..788	CDD:319316	17/78 (22%)
		Ig	795..888	CDD:325142
		Ig	902..993	CDD:325142
		Ig	1016..1094	CDD:325142
		Ig	1100..1192	CDD:325142
		Ig	1215..1293	CDD:325142
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910