DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-epsilon and ntm

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_004916061.1	Gene:	ntm / 100492453	XenbaseID:	XB-GENE-6045425	Length:	374	Species:	Xenopus tropicalis

Alignment Length:	358	Identity:	112/358 - (31%)
Similarity:	169/358 - (47%)	Gaps:	39/358 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 VISEDPEFTDVIENITVPAGRNVKLACSVKNLGSYKVAWMHFEQSAILTVHNHVITRNPRISVTH 111
            |.|.|..|...::|:||..|.:..|.|:|.|..: :|||::  :|.||...|...:.:||:.:..
Frog    32 VRSGDAGFPKAMDNVTVRQGDSAILRCTVDNRVT-RVAWLN--RSTILYTGNDKWSIDPRVVLLA 93

  Fly   112 DKHDKHRTWFLHINNVQEEDRGRYMCQINTVT-AKTQYGFVKVVVPPNIDDALTSSDIIVREGDN 175
            :...::.   :.|.||...|.|.|.|.:.|.. .||....:.|.|||.|.|  .||.|.|.||.|
Frog    94 NTKSQYS---IEIQNVDIYDEGPYTCSVQTDNHPKTSRVHLIVQVPPRIVD--ISSSIAVNEGSN 153

  Fly   176 VTLRCKAKGSPEPTIKWKRDDGNKIVINKTLEVHDLETDSLELERISRLHMGAYLCIASNGVPPS 240
            |:|.|.|.|.|||.:.|:       .::........|.:.||:..|:|...|.|.|.|||.|...
Frog   154 VSLICIANGRPEPVVNWR-------YLSPKARGFVSEDEYLEITGITREQSGIYECSASNDVSAP 211

  Fly   241 VSKRIKVSVDFSPMVWIPHQLVGIPIGFNITLECFIEANPTSLNYWTRENDQMITESSKYKTETI 305
            ..:|:|::|::.|.: :..|.:|.|:|....|:|...|.|.:..:|.:|:.::.......|.|
Frog   212 DVRRVKLTVNYPPYI-LDAQNIGAPLGHRGILQCEASAVPAADFFWYKEDKRLSDSWRGVKVE-- 273

  Fly   306 PGHPSYKATMRLTITNVQSSDYGNYKCVAKNPRGDMDGNIKLYMSSPPTTQPPPTTTTLRRTTTT 370
                :.:...|:|..||...|||||.|:|||..|..:.:|.|:.....|:.|      |.:..:|
Frog   274 ----NRETISRVTFLNVSEQDYGNYTCMAKNLLGHSNASIILFELFQSTSSP------LLQEEST 328

  Fly   371 AAEIALDGYINTPLNGNGIGIVGEGPTNSVIAS 403
            ||        .|||.|.  |.|.:|.:.|...|
Frog   329 AA--------LTPLKGP--GAVHDGNSGSTQCS 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	28/96 (29%)
		Ig	69..139	CDD:143165	20/69 (29%)
		IG_like	165..249	CDD:214653	30/83 (36%)
		IGc2	172..237	CDD:197706	23/64 (36%)
		IG_like	267..348	CDD:214653	24/80 (30%)
		Ig	270..339	CDD:299845	21/68 (31%)
ntm	XP_004916061.1	Ig	45..133	CDD:299845	27/93 (29%)
		IG_like	45..133	CDD:214653	27/93 (29%)
		IG_like	143..220	CDD:214653	30/83 (36%)
		IGc2	150..209	CDD:197706	23/65 (35%)
		ig	227..311	CDD:278476	27/89 (30%)
		IG_like	230..311	CDD:214653	27/86 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	58	1.000	Domainoid score	I10578
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H41139
Inparanoid	1	1.050	138	1.000	Inparanoid score	I4412
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	1	1.000	-	-		otm47726
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3058
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.090