DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-epsilon and iglon5

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_002938252.1	Gene:	iglon5 / 100488314	XenbaseID:	XB-GENE-945713	Length:	333	Species:	Xenopus tropicalis

Alignment Length:	309	Identity:	91/309 - (29%)
Similarity:	145/309 - (46%)	Gaps:	33/309 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 EFTDVIENITVPAGRNVKLACSVKNLGSYKVAWMHFEQSAILTVHNHVITRNPRIS-VTHDKHDK 116
            ||....:|.||..|.|..|:|.:.:..: :|||::  :|.||.......:.:.|:. :|:.|.:
Frog    28 EFVPPADNYTVSQGDNATLSCLIDDKVT-RVAWLN--RSNILYAGKDKWSIDSRVQLLTNTKSE- 88

  Fly   117 HRTWFLHINNVQEEDRGRYMCQINTV-TAKTQYGFVKVVVPPNIDDALTSSDIIVREGDNVTLRC 180
               :.:.|.:|...|.|.|.|...|. ...|...::.|.||..|.:  .||.:.|.||.||.|:|
Frog    89 ---YSIVITHVDVADEGLYTCSFQTEDKPHTSQVYLIVQVPAKIVN--ISSSVTVNEGSNVNLQC 148

  Fly   181 KAKGSPEPTIKWKRDDGNKIVINKTLEVHDLETDSLELERISRLHMGAYLCIASNGVPPSVSKRI 245
            .|.|.|||||.|:          :..|....|.:.||:..|:|...|.|.|:.||||....:|::
Frog   149 LAVGKPEPTITWQ----------QLSEGFSSEGELLEITEINRQQAGDYECVTSNGVSVPDTKKV 203

  Fly   246 KVSVDFSPMVWIPHQLVGIPIGFNITLECFIEANPTSLNYWTRENDQMI---TESSKYKTETIPG 307
            :::|::.|.: ...:....|:|...||.|...|.|.:...|.::..:.:   ||....|||:
Frog   204 QITVNYPPYI-TDVKNAQSPVGRPATLRCKAMAVPPAEFEWYKDEKRRLISGTEGLSIKTES--- 264

  Fly   308 HPSYKATMRLTITNVQSSDYGNYKCVAKNPRGDMDGNIKLYMSSPPTTQ 356
              |:..   :..:||.|..||||.|:|.|..|..:.:::|.....|..|
Frog   265 --SWSV---IVFSNVTSRHYGNYTCLASNKLGSFNSSLRLLKPGDPLNQ 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	25/97 (26%)
		Ig	69..139	CDD:143165	17/70 (24%)
		IG_like	165..249	CDD:214653	31/83 (37%)
		IGc2	172..237	CDD:197706	25/64 (39%)
		IG_like	267..348	CDD:214653	24/83 (29%)
		Ig	270..339	CDD:299845	22/71 (31%)
iglon5	XP_002938252.1	Ig	31..123	CDD:299845	24/98 (24%)
		IG_like	35..123	CDD:214653	24/94 (26%)
		Ig	126..207	CDD:299845	33/92 (36%)
		I-set	128..207	CDD:254352	32/90 (36%)
		I-set	210..299	CDD:254352	26/97 (27%)
		Ig	227..298	CDD:143165	23/78 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	58	1.000	Domainoid score	I10578
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	138	1.000	Inparanoid score	I4412
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.970