DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-epsilon and LOC100331810

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_002660992.3	Gene:	LOC100331810 / 100331810	-ID:	-	Length:	264	Species:	Danio rerio

Alignment Length:	239	Identity:	50/239 - (20%)
Similarity:	93/239 - (38%)	Gaps:	52/239 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   168 IIVREGD-----NVTLRCKAKGSP-------EPTIK-----------WKRDD----GNKIVINKT 205
            :::..||     |..:|.|: |||       |...|           |...:    ||:  ..|.
Zfish    10 VLLHIGDGAWVINQNIRVKS-GSPGIIPCPYEEQYKEHQKFWCQGYFWSTCNLLAFGNE--TGKN 71

  Fly   206 LEVHDLETDS---LELERISRLHMGAYLCIASNGVPPSVSK--RIKVSVDFSPMVWIPHQLVGIP 265
            ..:.|....|   :|.:.:.....|.|.|....|.|.::..  .:.::|..:|.|.:....|...
Zfish    72 FSITDYPAQSVFTVEWQNLQPSDSGHYWCAVEIGGPGTLDAGYYVYLTVQSAPDVSVMSSSVSGH 136

  Fly   266 IGFNITLECFIEANPTSLN-YWTRENDQ---MITESSKYKTETIPGHPSYKATMRLTITNVQSSD 326
            .|.|::::||..:...:.| .|.|..|:   .:..|...::.::......:::..:.:|.::.||
Zfish   137 EGGNVSVQCFYSSRYKAYNKQWCRVKDKSCYAVERSDTSQSSSVQISDDGESSFTVLMTGLRLSD 201

  Fly   327 YGNYKCVAKNPRGDMDGNIKLYMSSPP-----TTQPP----PTT 361
            .|.|    ....|::...::|.::.|.     ||||.    |||
Zfish   202 SGWY----FGSVGNLQVPVQLTVTKPEHKDLYTTQPSAKLIPTT 241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653
		Ig	69..139	CDD:143165
		IG_like	165..249	CDD:214653	22/112 (20%)
		IGc2	172..237	CDD:197706	20/94 (21%)
		IG_like	267..348	CDD:214653	15/84 (18%)
		Ig	270..339	CDD:299845	12/72 (17%)
LOC100331810	XP_002660992.3	IG_like	23..120	CDD:214653	19/99 (19%)
		Ig	35..106	CDD:299845	12/72 (17%)
		Ig	135..>205	CDD:299845	13/69 (19%)
		IG_like	137..220	CDD:214653	16/86 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	40	1.000	Domainoid score	I12510
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000