DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-epsilon and si:ch211-66e2.5

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_001920347.3	Gene:	si:ch211-66e2.5 / 100150500	ZFINID:	ZDB-GENE-131121-180	Length:	302	Species:	Danio rerio

Alignment Length:	246	Identity:	59/246 - (23%)
Similarity:	93/246 - (37%)	Gaps:	68/246 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 LNNVISEDPEFTDV-IENITVPA--GRNVKLACSVKNLG--SYKVAWMHFEQSAILTVHNHVITR 103
            ||.|:.:.|:...: :.|.:.|.  ||..:|.|.|.|:.  .|.|...:.||:   .|:||..:.
Zfish   100 LNLVLYKKPDSVSISLVNHSSPVVEGREYQLQCEVHNVAPVQYLVLRWYREQT---EVYNHSFSE 161

  Fly   104 ----NP-RISVTHDKHDKHRTWFLHINNVQEEDRGRYMCQINTVTAKTQYG-------------- 149
                .| ::|.|          .|.:.| :.||..:|.|:     |:.|.|
Zfish   162 LTPATPVQVSST----------LLIVPN-RAEDGAQYRCE-----AELQLGPEGPQPPPTVLSPS 210

  Fly   150 -FVKVVVPPNIDDALTSSDIIVREGDNVTLRCKAKGSPEPTIKWKRDDGNKIVINKTLEVHDLET 213
             .:.|..||:.... ....:.|.||..|.|.|.|:|:|.|...|...:..:            :.
Zfish   211 LNIAVHYPPDFRSP-KEEQLEVSEGSEVVLDCTAEGNPLPVYIWTSPNLQE------------KA 262

  Fly   214 DSLELERISRLHMGAYLCIASNGVPPSVSKRIKVSVDFSPMVWIPHQLVGI 264
            |...:.:.:.|..|.|.|.|||    .:.|:.|..|       |.|:..|:
Zfish   263 DDQPVLKDASLSPGVYTCTASN----ILGKKSKQFV-------IKHKSKGV 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	28/119 (24%)
		Ig	69..139	CDD:143165	20/76 (26%)
		IG_like	165..249	CDD:214653	21/83 (25%)
		IGc2	172..237	CDD:197706	18/64 (28%)
		IG_like	267..348	CDD:214653
		Ig	270..339	CDD:299845
si:ch211-66e2.5	XP_001920347.3	Ig	108..203	CDD:299845	28/113 (25%)
		IG_like	122..196	CDD:214653	24/92 (26%)
		IG_like	227..293	CDD:214653	21/81 (26%)
		Ig_2	227..284	CDD:290606	17/68 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910